Name of Trainee
(Years In Program)
*Training Grant eligible
**Training Grant supported

Lam, L
(9/1994-9/1999)

Articles on EPub

Dave SS, Fu K, Wright GW, Lam LT, Kluin P, Boerma EJ, Greiner TC,
Weisenburger DD, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne
RD, Delabie J, Rimsza LM, Braziel RM, Grogan TM, Campo E, Jaffe ES,
Dave BJ, Sanger W, Bast M, Vose JM, Armitage JO, Connors JM,
Smeland EB, Kvaloy S, Holte H, Fisher RI, Miller TP, Montserrat E,
Wilson WH, Bahl M, Zhao H, Yang L, Powell J, Simon R, Chan WC,
Staudt LM; Lymphoma/Leukemia Molecular Profiling Project. (2006).
Molecular diagnosis of Burkitt's lymphoma. N Engl J Med. 354(23):2431-42.

Shaffer AL, Wright G, Yang L, Powell J, Ngo V, Lamy L, Lam LT, Davis
RE, Staudt LM. (2006). A library of gene expression signatures to
illuminate normal and pathological lymphoid biology. Immunol Rev.
210:67-85.

Ngo VN, Davis RE, Lamy L, Yu X, Zhao H, Lenz G, Lam LT, Dave S, Yang
L, Powell J, Staudt LM. (2006). A loss-of-function RNA interference screen
for molecular targets in cancer. Nature. 441(7089):106-10.

Lam LT, Davis RE, Pierce J, Hepperle M, Xu Y, Hottelet M, Nong Y, Wen D,
Adams J, Dang L, Staudt LM. (2005). Small molecule inhibitors of IkappaB
kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma
defined by gene expression profiling. Clin Cancer Res. 11(1):28-40.

Lam LT and Bresnick EH. (2004). Gene array technology and the study of
platelets and megakaryocytes. Methods Molec Biol. 273:479-490. PMID:
15308819

Kovanen P, Rosenwald A, Hurt EM, Lam LT, Fu J, Staudt LM, and Leonard
WJ. (2001). Expression monitoring reveals highly redundant gene responses
to IL-2, IL-4, IL-7, and IL-15 and antigen receptor stimulation in lymphocytes.
Submitted to J. Immunol.

Lam LT, Pickeral O, Peng AC, Rosenwald A, Hurt EM, Giltnane JM, Averett
L, Zhao H, Davis RE, Sathyamoorthy M, Wahl E, Harris E, Mikovits J, Monks
A, Hollingshead M, Sausville EA, and Staudt LM. (2001). Genomic-scale
measurement of mRNA turnover using the anti-cancer drug flavopiridol.
GenomeBiology. 2/10/0041.

Lam LT, Ronchini C, Norton J, Capobianco AJ, and Bresnick EH. (2000).
Suppression of erythroid but not megakaryocytic differentiation of human
K562 erythroleukemic cells by Notch-1. J Biol Chem. 275:19676-19684.
PMID: 10783395

Lam LT and Bresnick EH. (1998). Identity of the b-globin locus control
region binding protein HS2NF5 as the mammalian homolog of the
Notch-regulated transcription factor suppressor of hairless. J Biol Chem.
273:24223-24231. PMID: 9727046

Bresnick EH, Versaw W, Lam LT, Forsberg EC, and Eisenman HC. (1998).
Activation at a distance: Nucleoprotein complexes that remodel chromatin.
In Gene Therapy and Molecular Biology: from Basic Mechanisms to Clinical
Applications (T. Boulikas, ed.)Edition 1, Gene Therapy Press, Palo Alto, pp.
483-494.

Forsberg EC, Lam LT, Yang XJ, Nakatani Y, and Bresnick EH. (1997).
Human histone acetyltransferase GCN5 exists in a stable macro-molecular
complex lacking the adapter ADA2. Biochem. 36:15918-15924. PMID: 9398325

Lam LT and Bresnick EH. (1996). A novel DNA binding protein, HS2NF5,
interacts with a functionally important sequence of the human b-globin locus
control region. J Biol Chem. 271:32421-32429. PMID: 8943307

Lam LT and Bresnick EH. (1995). Evidence for distinct DNA binding forms of
the erythroid-specific transcription factor NF-E2. Biochem. 34:16347-16358.
PMID: 8845360

Leonard, A.S.*
(9/1995-2/2001)

Articles on EPub

Leonard AS, Bayer KU, Merrill MA, Lim IA, Shea MA, Schulman H, and Hell JW. (2002). Regulation of calcium/calmodulin-dependent protein kinase I I docking to N-Methyl-D-aspartate receptors by calcium/calmodulin and a-actinin. J Biol Chem. 277:48441-48448. PMID: 12379661

Bayer KU, De Koninck P, Leonard AS, Hell JW, and Schulman H. (2001). Interaction with the NMDA receptor locks CaMKII in an active conformation.
Nature. 411:801-805. PMID: 11459059

Valtschanoff JG, Burett A, Davare MA, Leonard AS, Hell JW, and Weinberg
RJ. (2000). SAP97 concentrates at the postsynaptic density in cerebral cortex.
Eur J Neurosci. 12:3605-3614. PMID: 11029631

Leonard AS, Lim IA, Hemsworth DE, Horne MC, and Hell JW. (1999).
Calcium/calmodulin-dependent protein kinase II is associated with the
N-methyl-D-aspartate receptor. PNAS USA. 96:3239-3244. PMID: 10077668

Leonard AS, Davare MA, Horne MC, Garner CC, and Hell JW. (1998). SAP97 is associated with the a-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit. J Biol Chem. 273:19518-19524. PMID: 9677374

Leonard AS and Hell JW. (1997). Cyclic AMP-dependent protein kinase and
protein kinase C phosphorylate N-methyl-D-aspartate receptors at different sites.
J Biol Chem. 272:12107-12115. PMID: 9115280

Coleman JS and Leonard AS. (1995). Why it matters where a folivore feeds.
Oecologia. 101:324-328.

Sommer, J.A.*
(8/1995-11/2001)

Articles on EPub

Aga M, Watters JJ, Pfeiffer ZA, Wiepz GJ, Sommer JA, and Bertics PJ (2004).
Evidence for nucleotide receptor modulationof crosstalk between MAP kinase
NF-kB signaling pathways in murine RAW 264.7 macrophages. Am J
Physiology-Cell Physiology. 286:C923-930. PMID: 14684387

Guerra AN, Fisette PL, Pfeiffer ZA, Quinchia-Rios BH, Prabhu U, Aga M,
Denlinger LC, Guadarrama AG, Abozeid S, Sommer JA, Proctor RA, and Bertics
PJ. (2003). Purinergic receptor regulation of LPS-induced signaling and
pathophysiology. J Endotoxin Res. 9:256-263. PMID: 12935357

Denlinger LC, Sommer JA, Parker K, Gudipaty L, Fisette PL, Watters JW, Proctor
RA, Dubyak GR, and Bertics PJ. (2003). Mutation of a dibasic amino acid motif
within the C terminus of the P2X7 nucleotide receptor results in trafficking defects
and impaired function. J Immunol.171:1304-1311. PMID: 12874219

Sommer JA, Fisette PL, Hu Y, Denlinger LC, Guerra AN, Bertics PJ, and Proctor
RA. (1999). Purinergic receptor modulation of LPS-stimulated signaling events and
nitric oxide release in RAW 264.7 macrophages. J Endotoxin Res. 5:70-74.

Watters JJ, Sommer JA, Pfeiffer ZA, Prabhu U, Guerra AN, and Bertics PJ. (2002). A differential role for the mitogen-activated protein kinases in lipopolysaccharide
signaling: the MEK/ERK pathway is not essential for nitric oxide and interleukin 1b
production. J Biol Chem. 277:9077-9087. PMID: 11786532

Watters JJ, Sommer JA, Fisette PL, Pfeiffer ZA, Aga M, Prabhu U, Guerra AN,
Denlinger LC, and Bertics PJ. (2001). The P2X7 nucleotide receptor: modulation
of LPS-induced macrophage signaling and mediator production. Drug Dev Res.
53:91-104.

Denlinger LC, Fisette PL, Sommer JA, Watters JJ, Prabhu U, Dubyak GR, Proctor
RA, and Bertics PJ. (2001). Cutting edge: the nucleotide receptor P2X7 contains
multiple protein- and lipid-interaction motifs including a potential binding site for
bacterial lipopolysaccharide. J Immunol. 167:1871-1876. PMID: 11489964

Denlinger LC, Garis KA, Sommer JA, Guadarrama AG, Proctor RA, and Bertics PJ. (1998). Nuclear translocation of NF-b in lipopolysaccharide-treated macrophages fails to correspond to endotoxicity: evidence suggesting a requirement for an g interferon-like signal. Infection and Immunity. 66:1638-1647. PMID: 9529092

Thiriot, D.S.*
(9/1995-7/2001)

Articles on EPub

Thiriot DS, Nevzorov AA, and Opella SJ. (2005). Structural basis of the temperature transition of Pf1 bacteriophage. Protein Sci. 14:1064-1070.

Thiriot DS, Nevzorov AA, Zagyanskiy L, Wu CH, and Opella SJ. (2004). Structure of the coat protein in Pf1 bacteriophage determined by solid-state NMR spectroscopy. J Mol Biol. 341:869-879.

Mesleh MF, Lee S, Veglia G, Thiriot DS, Marassi F, and Opella SJ. (2003). Dipolar Waves Map the Structure and Topology of Helices in Membrane Proteins. J Am Chem Soc. 125:8928-8935.

Thiriot DS, Sievert MK, and Ruoho AE. (2002). Identification of human vesicle monoamine transporter (VMAT2) lumenal cysteines, which form an intramolecular disulfide bond. Biochem J. 41:6346-6353. PMID: 12009896

Wu Z, Thiriot DS, and Ruoho AE. (2001). Tyr199 in transmembrane domain 5 of the b2-adrenergic receptor interacts directly with the pharmacophore of a unique
fluorenone-based antagonist. Biochem J. 354:485-491. PMID: 11237852

Thiriot DS and Ruoho AE. (2001). Mutagenesis and derivatization of human vesicle monoamine transporter 2 (VMAT2) cysteines identify transporter domains involved in tetrabenazine binding and substrate transport. J Biol Chem. 276:27304-27315. PMID: 11375404

Rong Y, Arbabian M, Thiriot DS, Seibold A, Clark RB, and Ruoho AE. (1999). Probing the salmeterol binding site on the b2-adrenergic receptor using a novel photoaffinity ligand, [125I]-Iodoazidosalmeterol. Biochem. 38:11278-11286. PMID: 10471277

Sievert MK, Thiriot DS, Edwards RH, and Ruoho AE. (1998). High-efficiency expression and characterization of the synaptic-vesicle monoamine translocator from baculovirus-infected insect cells. Biochem J. 330:959-966. PMID: 9480916

Davare, M.A.**
(9/1996-8/2000)

Articles on EPub

Atkins CM, Davare MA, Oh MC, Derkach V, and Soderling TR.  (2005). Bidirectional regulation of cytoplasmic polyadenylation element-binding protein phosphorylation by Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 1 during hippocampal long-term potentiation. J Neurosci. 25:5604-5610.

Davare MA, Saneyoshi T, Guire ES, Nygaard SC, and Soderling TR. (2004). Inhibition of calcium/calmodulin-dependent protein kinase kinase by protein 14-3-3.  J Biol Chem.

Simon J, Arthur C, Fong AL, Dwyer JM, Davare M, Reese E, Obrietan K, and Impey S. (2004). Mitogen- and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins. J Neurosci. 24:4324-4332.

Wayman GA, Kaech S, Grant WF, Davare M, Impey S, Tokumitsu H, Nozaki N, Banker G, and Soderling TR. (2004). Regulation of axonal extension and growth cone motility by calmodulin-dependent protein kinase I. J Neurosci. 24:3786-3794.

Cottom J, Salvador LM, Maizels ET, Reierstad S, Park Y, Carr DW, Davare MA, Hell JW, Palmer SS, Dent P, Kawakatsu H, Ogata M, and Hunzicker-Dunn M. (2003). Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase. J Biol Chem 278:7167-7179. PMID: 12493768

Davare MA and Hell JW. (2003). Increased phosphorylation of the neuronal L-type Ca(2+) channel Ca(v)1.2 during aging. PNAS USA. 100:16018-16023. PMID: 14665691

Davare MA, Avdonin V, Hall DD, Peden EM, Burette A, Weinberg RJ, Horne MC, Hoshi T, and Hell JW. (2001). A b2 adrenergic receptor-signaling complex assembled with the Ca2+ channel Cav1.2. Science. 293:98-101. PMID: 11441182

Valtschanoff JG, Burett A, Davare MA, Leonard AS, Hell JW, and Weinberg RJ. (2000). SAP97 concentrates at the postsynaptic density in cerebral cortex. Eur J Neurosci. 12:3605-3614. PMID: 11029631

Davare MA, Horne MC, and Hell JW. (2000). Protein phosphatase 2A is associated with class C L-type calcium channels (Cav1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase. J Biol Chem. 275:39710-39717. PMID: 10984483

Davare MA, Dong F, Rubin CS, and Hell JW. (1999). The A-kinase anchor protein MAP2B and cAMP-dependent protein kinase are associated with class C L-type calcium channelsin neurons. J Biol Chem. 274:30280-30287. PMID: 10514522

Leonard AS, Davare MA, Garner CC, Horne MC, and Hell JW. (1998). SAP97 is associated with the a-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit. J Biol Chem. 273:19518-19524. PMID: 9677374

Eisenman, H.C.*
(9/1996-1998)

Articles on EPub

Bresnick E, Versaw W, Lam LT, Forsberg EC, and Eisenman HC. (1998). Activation at a distance: Nucleoprotein complexes that remodel chromatin. In Gene Therapy and Molecular Biology: from Basic Mechanisms to Clinical Applications (T. Boulikas, ed.) Edition 1, Gene Therapy Press, Palo Alto, pp. 483-494.

Eisenman HC and Craig EA. (2004). Activation of pleiotropic drug resistance by the J-protein and Hsp70-related proteins, Zuo1 and Ssz1. Mol Microbiol. 53(1):335-44

Craig EA, Eisenman HC, and Hundley HA. (2003). Ribosome-tethered molecular chaperones: the first line of defense against protein misfolding. Curr Opin Microbiol. 6(2):157-62

Forsberg, E.C.
(1996-2001)

Articles on EPub

Forsberg EC, Serwold T, Kogan S, Weissman IL, and Passegu. (2006). New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. Cell. 126(2):415-26.

Forsberg EC, Prohaska SS, Katzman S, Heffner GC, Stuart JM, and Weissman IL. (2005). Differential expression of novel potential regulators in hematopoietic stem cells. PLoS Genet.1(3):e28.

Forsberg EC and Bresnick EH. (2001). Histone acetylation beyond promoters: long-range acetylation patterns in the chromatin world. Bioessays. 23:820-830. PMID: 11536294

Forsberg EC, Downs KM, and Bresnick EH. (2000). Direct interaction of NF-E2 withhypersensitive site 2 of the b-globin locus control region in living cells. Blood. 96:334-339. PMID: 10891470

Forsberg EC, Downs KM, Christensen HM, Im HM, Nuzzi PA, and Bresnick EH. (2000). Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain. PNAS USA. 97:14494-14499. PMID: 11121052

Forsberg EC, Zaboikina TN, Versaw WK, Ahn NG, and Bresnick EH. (1999). Enhancementof b-globin locus control region-mediated transactivation by mitogen-activated protein kinasesthrough stochastic and graded mechanisms. Mol Cell Biol. 19:5565-5575. PMID: 10409746

Forsberg EC, Johnson K, Zaboikina TN, Mosser EA, and Bresnick EH. (1999). Requirement of an E1A-sensitive coactivator for long-range transactivation by the b-globin locus control region. J Biol Chem. 274:26850-26859. PMID: 10480893

Mosser EA, Kasanov JD, Forsberg EC, Kay BK, Ney PA, and Bresnick EH. (1998). Physical and functional interactions between the transactivation domain of the hematopoietic transcription factor NF-E2 and WW domains. Biochem. 37:13686-13695. PMID: 9753456

Bresnick EH, Versaw W, Lam LT, Forsberg EC, and Eisenman HC. (1998). Activation at a distance: Nucleoprotein complexes that remodel chromatin. In Gene Therapy and Molecular Biology: from Basic Mechanisms to Clinical Applications (T. Boulikas, ed.) Edition 1, Gene Therapy Press, Palo Alto, pp. 483-494.

Forsberg EC, Lam LT, Yang XJ, Nakatani Y, and Bresnick EH. (1997). Human histone acetyltransferase GCN5 exists in a stable macromolecular complex lacking the adapter ADA2. Biochem. 36:15918-15924. PMID: 9398325

McDearmon, E*
(Blondell)
(9/1996-6/2001)

Articles on EPub

McDearmon E, Combs A, Sekiguchi K, and Ervasti J. (2006). Brain a-Dystroglycan displays unique glycoepitopes and preferential binding to Laminin-10/11. FEBS Letters. 580:3381-3385. PMID: 16709410

McDearmon EL, Combs AC, and Ervasti JM. (2003). Core 1 glycans on a-dystroglycan mediate laminin-induced acetylcholine receptor clustering but not laminin binding. J Biol Chem. 278:44868-44873. PMID: 12952987

Smirnov SP, McDearmon EL, Li S, Ervasti J, Tryggvason K, and Yurchenco PD. (2002). Contributions of the LG modules and furin-processing to laminin-2 functions. J Biol Chem. 277:18928-18937. PMID: 11886875

McDearmon EL, Combs AC, and Ervasti JM. (2001). Differential Vicia villosa agglutinin reactivity identifies three distinct dystroglycan complexes in skeletal muscle. J Biol Chem. 276:35078-35086. PMID: 11459841

McDearmon EL, Burwell AL, Combs AC, Renley BA, Sdano MT, and Ervasti JM. (1998). Differential heparin sensitivity of a-dystroglycan binding to laminins expressed in normal and dy/dy mouse skeletal muscle. J Biol Chem. 273:24139-24144. PMID: 9727035

Burbach, B.J.**
(9/1997-7/2004)

Articles on EPub

Burbach BJ, Mueller K, O'Gorman W, Peterson EJ, and Shimizu Y. (2006). ADAP and SKAP55 are coordinately required for efficient antigen dependent LFA-1 function on primary naïve murine T cells. Manuscript in preparation.

Medeiros RB, Burbach BJ, Mueller K, Highfill S, Peterson E, and Shimizu Y. (2006).  Association of ADAP with Carma1 controls NFkB activation in T cells. Submitted, Science.

Fostel LV, Dluzniewska J, Shimizu Y, Burbach BJ, and Peterson EJ. (2006). ADAP is dispensible for natural killer cell development and function. Manuscript in Revision, International Journal of Immunology, January 2006.

McQuade KJ, Beauvais DM, Burbach BJ, and Rapraeger AC. (2006). Syndecan-1 regulates anb3 integrin activity in B82L fibroblasts. J Cell Sci. 119:2445-2456. PMID: 16720645

Beauvais DL, Burbach BJ, and Rapraeger AC. (2004). Syndecan-1 ectodomain regulates anb3 integrin activity in human mammary carcinoma cells. J Cell Biol. 167:171-181. PMID: 15479743

Burbach BJ, Ji Y, and Rapraeger AC. (2004). Syndecan-1 ectodomain regulates
matrix-dependent signaling in human breast carcinoma cells. Exp Cell Res. 300:234-247

Burbach BJ, Friedl A, Mundhenke CH, and Rapraeger AC. (2003). Syndecan-1 accumulates in lysosomes of poorly differentiated breast carcinoma cells. Matrix Biology. 22(2):163-77.

Brown LM, Burbach BJ, McKenzie BA, and Connell GJ. (1999). A Cis-acting A-U sequence element induces kinetoplastid U-insertions. J Biol Chem. 274:6295-6304.

Knight, S.M.*
(9/1997-9/2002)

Articles on EPub

Knight SM, Umezawa N, Lee HS, Gellman SH, and Kay BK. (2002). A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction. Anal Biochem. 300:200-236. PMID: 11779115

Kay BK, Kasanov J, Knight SM, and Kurakin A. (2000). Convergent evolution with combinatorial peptides. FEBS Lett. 480:55-62. PMID: 10967329

Lim, I.A.*
(9/1997-1/2003)

Articles on EPub

Lim IA, Merrill MA, Chen Y, and Hell JW. (2003). Disruption of the NMDA receptor-PSD-95
interaction in hippocampal neurons with no obvious physiological short-term effect.
Neuropharmacology. 45:738-754. PMID: 14529713

Seabold GK, Burette A, Lim IA, Weinberg RJ, and Hell JW. (2003). Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the SH3 domains of PSD-95 and SAP102. J Biol Chem. 278:15040-15048. PMID: 12576483

Lim IA, Hall DD, and Hell JW. (2002). Selectivity and promiscuity of the first and second PDZ domains of PSD-95 and SAP102. J Biol Chem. 277:21697-21711. PMID: 11937501

Leonard AS, Bayer KU, Merrill MA, Lim IA, Shea MA, Schulman H, and Hell JW. (2002). Regulation of CaMKII docking to NMDA receptors by calcium/calmodulin and a-actinin. J Biol Chem. 277:48441-48448. PMID: 12379661

Leonard AS, Lim IA, Hemsworth DE, Horne MC, and Hell JW. (1999).
Calcium/calmodulin-dependent protein kinase II is associated with the N-methyl-D-aspartate receptor. PNAS USA 96:3239-3244. PMID: 10077668

Bhatt, A.K.**
(9/1998-2002)

Articles on EPub

Bhatt A, Nandipati K, Dhar N, Ulchaker J, Jones S, Rackley R, Zippe C. (2006). Neurovascularpreservation in orthotopic cystectomy: impact on female sexual function. Urology. 67(4):742-5.

Dhar NB, Bhatt A, Jones JS. (2006). Determining the success of vasectomy. BJU Int 97:773-776.

Bhatt AK and Huttenlocher A. (2003). Dynamic imaging of cell-substrate contacts. Methods Enzymol. 361:337-352. PMID: 12624919

Bhatt AK, Kaverina I, Otey C, and Huttenlocher A. (2002). Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain. J Cell Sci. 115:3415-3425. PMID: 12154072

Dourdin N, Bhatt AK, Dutt P, Greer PA, Arthur JS, Elce JS, and Huttenlocher A. (2001). Reduced cell migration and disruption of the actin cytoskeleton in calpain-deficient embryonic fibroblasts. J Biol Chem. 276:48382-48388. PMID: 11602605

Lin B, Skidmore JM, Bhatt AK, Pfeffer SM, Pawloski L, and Maddock JR. (2001). Alanine scanmutagenesis of the switch I domain of the Caulobacter crescentus CgtA protein reveals criticalamino acids required for in vivo function. Mol Microbiol. 39:924-934. PMID: 11251813

Cho, Y.C.
(1998-2003)

Articles on EPub

Cho YC, Zheng W, Yamamoto M, Liu X, Hanlon PR, and Jefcoate CR. (2005). Differentiation of pluripotent C3H10T1/2 cells rapidly elevates CYP1B1 through a novel process that overcomes a loss of Ah Receptor. Arch Biochem Biophys. 439:139-153. PMID: 15967407

Hanlon PR, Cimafranca MA, Liu X, Cho YC, and Jefcoate CR. (2005). Microarray analysis of early adipogenesis in C3H10T1/2 cells: cooperative inhibitory effects of growth factors and 2,3,7,8-tetrachloro-dibenzo-p-dioxin. Toxicol Appl Pharmacol. 207:39-58. PMID: 16054899

Cho YC and Jefcoate CR. (2004). PPARg1 Synthesis and adipogenesis in C3H10T1/2 cells depends on S-Phase progression, but does not require mitotic clonal expansion. J Cell Biochem. 91:336-353. PMID: 14743393

Cho YC, Zheng W, and Jefcoate CR. (2004). Disruption of cell-cell contact maximally but transiently activates AhR-mediated transcription in 10T1/2 fibroblasts. Toxicol Appl Pharmacol. 199:220-238. PMID: 15364539

Hanlon PR, Ganem LG, Cho YC, Yamamoto M, and Jefcoate CR. (2003). AhR- and ERK-dependent pathways function synergistically to mediate 2,3,7,8-tetrachlorodibenzo-p-dioxin suppression of peroxisome proliferator-activated receptor-g1 expression and subsequent adipocyte differentiation. Toxicol Appl Pharmacol. 189:11-27. PMID: 12758056

Hayes, K.R.**
(9/1998-8/2004)

Articles on EPub

Hayes KR, Baggs JE, Hogenesch JB. (2005). Circadian clocks are seeing the systems biology light. Genome Biology. 6:219.

Hayes KR, Vollrath AL, Zastrow GM, McMillan BJ, Craven M, Jovanovich S, Rank DR, Penn S, Walisser JA, Reddy JK, Thomas RS, and Bradfield CA. (2005). EDGE: A Centralized Resource for the Comparison, Analysis, and Distribution of Toxicogenomic Information. Mol Pharmacol. 67:1360-1368.

Hayes KR and Bradfield CA. (2005). Advances in toxicogenomics. Chem Res Toxicol. 18:403-414.

Thomas RS, Rank DR, Penn SG, Zastrow GM, Hayes KR, Hu T, Pande K, Lewis M, Jovanovich SB, and Bradfield CA. (2002). Application of genomics to toxicology research. Environ Health Perspect. 110:919-923.

Thomas RS, Hayes KR, Zastrow GM, Tran K, Penn SG, Rank DR, and Bradfield CA. (2002). Application of DNA microarrays for predicting toxicity and evaluation cross-species extrapolation. In Toxicogenomics (T. Inoue and W.D. Pennie, Eds.) pp. 31-38. Springer-Verlag, Tokyo.

Thomas RS, Rank DR, Penn SG, Zastrow GM, Hayes KR, Pande K, Glover E, Silander T, Craven MW, Reddy JK, Jovanovich SB, and Bradfield CA. (2001). Identification of toxicologically predictive gene sets using cDNA microarrays. Mol Pharmacol. 60:1189-1194.

Holden, J.H.*
(Kloda)
(9/1998-5/2003)

Articles on EPub

Holden JH and Czajkowski C. (2006). Agonist-, antagonist-, and benzodiazepine-induced structural changes in the a1Met113-Leu132 region of the GABA-A receptor. (In press) Mol Pharmacol.

Holden JH and Czajkowski C. (2006). Residues in the a1M113-a1D123 region of the GABAA receptor mediate the actions of GABA and SR-95531 and are conformationally sensitive to allosteric modulation. Submitted J Biol Chem.

Holden JH and Czajkowski C. (2005). a1G124-a1L132: a novel binding site region on the GABAA receptor that undergoes different conformational rearrangements during ligand binding and allosteric modulation. In preparation

Holden JH and Czajkowski C. (2005). The GABAA receptor_a1H109-a1T112 region: a linker segment that participates in allosteric coupling of the GABA and benzodiazepine binding sites. In preparation

Holden JH and Czajkowski C. (2002). Different residues in the GABAA receptor a1T60-a1K70 region mediate GABA and SR-95531 actions. J Biol Chem. 277:18785-18792.

Huang, T.T.**
(9/1998-6/2003)

Articles on EPub

Huang TT, Davis S, Wu Z, and Miyamoto S. (2003). Sequential modification of NEMO-kB activation by genotoxic stress. Cell 115:565-576.

Huang TT, Feinberg S, Suryanarayanan S, and Miyamoto S. (2002). The zinc-finger domain of NEMO is selectively required for NF-kB activation by ultraviolet radiation and topoisomerase inhibitors. Mol Cell Biol 22:5813-5825.

Huang TT and Miyamoto S. (2001). Post-repression activation of NF-kB requires the amino-terminal nuclear export signal specific to IkBa. Mol Cell Biol. 21:4737-4747.

Huang TT, Kudo N, Yoshida M, and Miyamoto S. (2000). A nuclear export signal in the N-terminal regulatory domain of IkBa controls cytoplasmic localization of inactive NF-kB/IkBa complexes. PNAS USA. 97:1014-1019.

Huang TT, Wuerzberger-Davis SM, Seufzer BJ, Shumway SD, Kurama T, Boothman DA, and Miyamoto S. (2000). NF-kB activation by camptothecin: a linkage between nuclear DNA damage and cytoplasmic signaling events. J Biol Chem. 275:9501-9509.

Tsukamoto T, Yoo J, Hwang SI, Guzman RC, Hirokawa Y, Chou YC, Olatunde S, Huang TT, Bera TK, Yan J, and Nandi S. (2000). Expression of MAT1/PEA15 mRNA isoforms during physiological and neoplastic changes in the mouse mammary gland. Cancer Lett. 149:105-113.

Miyamoto S, Huang TT, Wuerzberger-Davis S, Bornmann WG, Pink JJ, Tagliarino C, Kinsella TJ, and Boothman DA. (2000). Cellular and molecular responses to topoisomerase I poisons: Exploiting synergy for improved radiotherapy. Ann NY Acad Sci. 922:274-292.

Tsukamoto T, Huang TT, Guzman RC, Chen X, Pascual RV, Kiamura T, and Nandi S. (1999). Isolation of oncogenes from rat mammary tumors by a highly efficient retrovirus expression cloning system. Biochem Biophys Res Commun. 265:7-12.

Bera TK, Tsukamoto T, Panda DK, Huang TT, Guzman RC, Hwang SI, and Nandi S. (1998). Defective retrovirus insertion activations c-Ha-ras protooncogene in an MNU-induced rat mammary carcinoma. Biochem Biophys Res Commun. 248:835-840.

Swanson SM, Guzman RC, Tsukamoto T, Huang TT, Dougherty CD, and Nandi S. (1996). N-Ethyl-N-nitrosourea induces mammary cancers in the pituitary-isografted mouse which are histologically and genotypically distinct from those induced by N-methyl-N-nitrosourea. Cancer Lett. 102:159-165.

Peden, E.M.*
(9/1998-12/2004)

Articles on EPub

Peden EM and Barr MM. (2005). The KLP-6 kinesin is required for male mating behaviors and polycystin localization in Caenorhabditis elegans. Curr Biol. 15:394-404.

Davare MA, Avdonin V, Hall DD, Peden EM, Burette A, Weinberg RJ, Horne MC, Hoshi T, and Hell JW. (2001). A b2 adrenergic receptor-signaling complex assembled with the Ca2+ channelCa(v)1.2. Science. 293:98-101. PMID: 11441182

Peden EM and Sweazey RD. (1999). Chemical stimulation of the larynogpharynx increases Fos-like immunoreactivity in the rat hypothalamus and amygdala. Brain Res Bull 48:629-639.

Seabold, G.K.*
(9/1998-8/2003)

Articles on EPub

Wang CY, Chang K, Petralia RS, Wang YX, Seabold GK, and Wenthold RJ. (2006). A novel family of adhesion-like molecules that interacts with the NMDA receptor. J Neurosci. 26:2174-83.

Seabold GK, Burette A, Lim IA, Weinberg RJ, and Hell JW. (2003). Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the SH3 domains of PSD-95 and SAP102. J Biol Chem. 278:15040-15048. PMID: 12576483

Seabold GK, Luo J, and Miller MW. (1998). Effect of ethanol on neurotrophin-mediated cell survival and receptor expression in cultures of cortical neurons. Dev Brain Res.108:139-145.

Beauvais, D.M.**
(9/1999-9/2005)

Articles on EPub

McQuade KJ*, Beauvais DM*, Burbach BJ, and Rapraeger AC. (2006). Syndecan-1 regulates avb5 integrin activity in B82L fibroblasts. J Cell Sci. 119:2445-2456. (* Co-first authors) PMID: 16720645

Beauvais DM, Burbach BJ, and Rapraeger AC. (2004). Syndecan-1 ectodomain regulates anb3 integrin activity in human mammary carcinoma cells. J Cell Biol. 167:171-181.

Beauvais DM and Rapraeger AC. (2004). Syndecans in tumor cell adhesion and signaling. Reprod Biol Endocrinol. 2:3-15. PMID 14711376

Beauvais DM and Rapraeger AC. (2003). Syndecan-1 mediated cell spreading requires signaling by avb3 integrins in human breast carcinoma cells. Exp Cell Res. 286:219-232.

Chang P.Y.
(9/2000-1/2006)

Articles on EPub

Chang PY and Miyamoto S. (2006). NFKB1 is a direct target of the TAL1 oncoprotein in human T leukemia cells. Cancer Res. 66:6008-6013.

Chang PY and Miyamoto S. (2006). Abstract nuclear factor-kB dimer exchange promotes a p21 (waf1/cip1) superinduction response in human T leukemic cells. Mol Cancer Res. 4:101-112.

Wuerzberger-Davis SM, Chang PY, Berchtold C, and Miyamoto S. (2005). Enhanced G2-M arrest by nuclear factor-kB-dependent p21waf1/cip1 induction. Mol Cancer Res. 3:345-353.

Manos EJ, Kim ML, Kassis J, Chang PY, Wells A, and Jones DA. (2001).
Dolichol-phosphate-mannose-3 (DPM3)/prostin-1 is a novel phospholipase C-g regulated gene negatively associated with prostate tumor invasion. Oncogene. 20:2781-2790.

Hannah, B.L.**
(Cordes)
(9/2000-5/2004)
MD,PhD

Articles on EPub

Carlson CB, Bernstein DA, Annis DS, Misenheimer TM, Hannah BL, Mosher DF, and Keck JL. (2005). Structure of the calcium-rich signature domain of human thrombospondin-2. Nat Struct Mol Biol. 12:910-914.

Hannah BL, Misenheimer TM, Pranghofer MM, and Mosher DF. (2004). A polymorphism in
thrombospondin-1 associated with familial premature coronary artery disease alters Ca2+ binding. J Biol Chem. 279:51915 –51922.

Misenheimer TM, Hannah BL, Annis DS, and Mosher DF. (2003). Interactions among the three structural motifs of the C-terminal region of human thrombospondin-2. Biochem. 42:5125-5132.

Hannah BL, Misenheimer TM, Annis DS, and Mosher DF. (2003). A polymorphism in
thrombospondin-1 associated with familial premature coronary heart disease causes a local change in conformation of the Ca2+-binding repeats. J Biol Chem. 278:8929-8934.

Im, H
(2000-2006)

Articles on Epub

Bresnick EH, Johnson KD, Kim SI and Im H. (2006). Establishment and regulation of chromatin domains: Mechanistic insights from studies of hemoglobin synthesis. Progress Nucleic Acid Research Mol Biol. 81:431-467. PMID: 16891178

Im H, Grass JA, Johnson KD, Kim SI, Boyer ME, Imbalzano AN, Bieker JJ, and Bresnick EH. (2005). Chromatin domain activation via GATA-1 utilitzation of a small subset of dispersed GATA motifs within a broad chromosomal region. PNAS USA. 102:17065-17070. PMID: 16286657

Im H*, Grass JA* Johnson KD, Boyer ME, Wu J, and Bresnick EH. (2004). Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation. Methods Mol Biol: Signal Transduction Protocols. 284:129-146. (*co-first authors) PMID: 15173613

Im H, Park C, Feng Q, Johnson KD, Kiekhaefer CM, Choi K, Zhang Y, and Bresnick EH. (2003). Dynamic regulation of histone H3 methylated at lysine 79 within a tissue-specific chromatin domain. J Biol Chem. 278:18346-18352. PMID: 12604594

Bresnick EH, Im H, and Johnson KD. (2003). Histone acetylation: long range patterns in the genome. Encyclopedia of the Human Genome, Nature Publishing Company pg 260-264, 1st edition.

Johnson KD, Grass JA, Park C, Im H, Choi K, and Bresnick EH. (2003). Highly restricted localization of RNA polymerase II within a locus control region of a tissue-specific chromatin domain. Mol Cell Biol. 23:6488-6493. PMID: 12944475

Khattak S, Im H, Park T, Ahnn J, and Spoerel NA. (2002). dELL, a drosophila homologue of transcription elongation factor ELL (Eleven-nineteen Lysine rich Leuke) is required for early development. Cell Biochem Funct. 20:119-127.

Im H, Grass JA, Christensen HM, Perkins A, and Bresnick EH. (2002). Histone
deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain. Biochem. 41:15152-15160. PMID: 124847

Forsberg EC, Downs KM, Christensen HM, Im H, Nuzzi PA, and Bresnick EH. (2000). Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain. PNAS USA. 97:14494-14499.

Wang, P
(9/2000-5/2005)

Articles on Epub

Wang, P, Chicka, MC, Bhalla, A, Richards, DA and Chapman ER. (2005). Synaptotagmin VII is targeted to secretory organelles in PC12 cells where it functions as a high affinity calcium sensor. Mol Cell Biol. 25:8693-8702.

Hui E, Bai J, Wang P, Sugimori M, Llinas R, and Chapman ER. (2005). Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis. PNAS USA. 102:5210-5214.

Wang P, Wang CT, Bai J, Jackson MB, and Chapman ER. (2003). Mutations in the effectorbinding loops in the C2A and C2B domains of synaptotagmin I disrupt exocytosis in a non-additive manner. J Biol Chem. 278:47030-47037.

*Bai J, *Wang P, and Chapman ER. (2002). C2A activates a cryptic Ca2+-triggered membrane penetration activity within the C2B domain of synaptotagmin I. PNAS USA. 99:1665-1670. *equal contribution.

*Earles C, *Bai J, Wang P, and Chapman ER. (2001). The tandem C2 domains of synaptotagmin contain redundant Ca2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis. J Cell Biol. 154:1117-1123. *equal contribution.

Zhao, B.M.**
(2000-2001)

Articles on EPub

Zhao BM and Hoffmann FM. (2006). Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA. Mol Biol Cell. 17:3819-31

Cui Q, Lim SK, Zhao B, and Hoffmann FM. (2005). Selective inhibition of TGF-beta responsive genes by Smad-interacting peptide aptamers from FoxH1, Lef1 and CBP. Oncogene. 24:3864-74.

Johnson KD, Christensen HM, Zhao B, and Bresnick EH. (2001). Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter. Mol Cell 8:465-471.

Cho, J
(9/2001-1/2006)

Articles on EPub

Cho J and Mosher DF. (2006). Enhancement of thrombo-genesis by plasma fibronectin crosslinked to fibrin and assembled in platelet thrombi. Blood. 107:3555-3563.

Cho J and Mosher DF. (2006). Characterization of fibronectin assembly by platelets adherent to adsorbed laminin-111. J Thromb Haemost. 4:943-951.

Cho J and Mosher DF. (2006). Impact of fibronectin assembly on platelet thrombus formation in response to type I collagen and von Willebrand factor. Blood.

Cho J, Degen JL, Coller BS, and Mosher DF. (2005). Fibrin but not adsorbed fibrinogen supports fibronectin assembly by spread platelets: effects of the interaction of aIIbb3 with the C-terminus of the fibrinogen g-chain. J Biol Chem. 280:35490-35498.

Cho J, Yun CH, Seo HS, Koga T, Dan T, Koo BA, and Kim HY. (2001). The antithrombotic efficacy of AT-1459, a novel, direct thrombin inhibitor, in rat models of venous and arterial thrombosis. Thromb Haemost. 86:1512-1520.

Cho JH, Seo H, Yun C, Koo B, Yoshida S, Koga T, Dan T, and Kim HY. (2000). In vitro and in vivo studies of AT-1362, a newly synthesized and orally active inhibitor of thrombin. Thromb Res. 100:97-107.

Jasuja, R
(9/2001-7/2006)

Articles on EPub

Jasuja R, Ge G, Voss NG, Lyman-Gingerich J, Branam AM, Pelegri FJ, and Greenspan DS. (2007). Bone morphogenetic protein 1 prodomain specifically binds and regulates signaling by bone morphogenetic proteins 2 and 4. J Biol Chem. 282:9053-9062.  PMID 17255107

Jasuja R, Voss N, Ge G, Hoffman GG, Lyman-Gingerich J, Pelegri F, and Greenspan DS. (2006). bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axis. Mech Dev. 123:548-558. PMID 16824737

Jasuja R, Allen BL, Pappano WN, Rapraeger AC, and Greenspan DS. (2004). Cell surface heparan sulfate proteoglycans potentiate chordin antagonism of bone morphogenetic protein signaling and are necessary for cellular uptake of chordin. J Biol Chem. 279:51289-51297.

Velpandian T, Jasuja R, Bhardwaj RK, Jasiwal J, and Gupta SK. (2001). Piperine in food: interference in the pharmacokinetics of phentoin. Eur J Drug Metab Pharmacokinet. 26:241-247.

Martowicz, M.L.*
(9/2001-6/2006)

Articles on EPub

Grass JA, Jing H, Kim SI, Martowicz ML, Pal S, Blobel GA, and Bresnick EH. (2006). Distinct functions of dispersed GATA factor complexes at an endogenous gene locus. Mol Cell Biol. 26:7056-7067. PMID: 16980610

Martowicz ML, Grass JA, and Bresnick EH. (2006). GATA-1-mediated transcriptional repression yields persistent transcription factor IIB - chromatin complexes. J Biol Chem. PMID: 16963445

Martowicz ML, Grass JA, Boyer ME, Guend H, and Bresnick EB. (2005). Dynamic GATA factor interplay at a multi-component regulatory region of the GATA-2 locus. J Biol Chem. 280:1724-1732. PMID: 15494394

Bresnick EH, Martowicz ML, Pal S, and Johnson KD. (2005). Developmental control via GATA factor interplay at chromatin domains. J Cell Physiol. 205:1-9. Review.

Wagner CT, Martowicz ML, Conner J, and Livesy SA. (2002). Biochemical stabilization enhances red blood cell recovery and stability following cryopreservation. Cryobiology. 45:153-166.

Venkataraman, S
(Kumar)
(9/2001-3/2006)

Articles on EPub

Kumar S, Dodson GE, Trinh A, Puchalski JR, and Tibbetts RS. (2005). ATR activation necessary but not sufficient for p53 Induction and apoptosis in Hydroxyurea-hypersensitive myeloid leukemia cells. Cell Cycle 4. 11:1665-1668. 

Shi Y, Venkataraman S, Dodson GE, Mabb AM, LeBlanc S, and Tibbetts RS. (2004). Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress. PNAS USA. 101:5898-5903.

Wilson, S**
(9/2001-12/2006)
MD/PhD

Articles on EPub

Kang, M
(9/2001-12/2005)

Articles on EPub

Kang M and Walker JW. (2006). Endothelin-1 and PKC induce positive inotropy without affecting pHi in ventricular myocytes. Exp Biol Med. 231:865-870. PMID 16741014

Robia SL, Kang M, and Walker JW. (2005). A novel determinant of PKC-e anchoring at cardiac Z-lines. Am J Physiol Heart Circ Physiol. 289:H1941-1950.

Kang M and Walker JW. (2005). Protein kinase C d and e mediate positive inotropy in adult ventricular myocytes. J Mol Cell Cardiol .38:753-764.

Carbonara, C*
(9/2002-8/2005)

Articles on EPub

Bairstow SF, Ling K, Su X, Firestone AJ, Carbonara C, and Anderson RA. (2006). Type Ig661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis. J Biol Chem. 281:20632-20642. PMID: 16707488

Ling K, Bairstow SF, Carbonara C, Turbin DA, Huntsman DG, and Anderson RA. (2007). Type Ig PIP kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with m1B adaptin. Submitted.

Fowler, A.M.**
(2001-2005)
Pharmacology Minor
MD/PhD

Articles on EPub

Fowler AM, Solodin NM, Valley CC, and Alarid ET. (2005). Altered target gene regulation controlled by estrogen receptor-a concentration. Mol Endocrinol. 20:291-301.

Valley CC, Metivier R, Solodin NM, Fowler AM, Mashek MT, Hill L, and Alarid ET. (2005). Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus. Mol Cell Biol. 25:5417-5428.

Valley CC, Metivier R, Solodin NM, Fowler AM, Mashek MT, Hilll L, and Alarid ET. (2005). Differential regulation of estrogen-inducible proteolysis and transcription by the estrogen receptor alpha N terminus. Mol Cel Biol 13:5417-5428.

Fowler AM, Solodin N, Preisler-Mashek MT, Zhang P, Lee AV, and Alarid ET. (2004). Increases in estrogen receptor-a concentration in breast cancer cells promote serine 118/104/106-independent AF-1 transactivation and growth in the absence of estrogen. FASEB J. 18:81-93.

Fowler AM and Alarid ET. (2004). Nuclear receptor and transcriptional complex cycles. Sci STKE. 262:11.

Fowler AM and Alarid ET. (2004). Dynamic control of nuclear receptor transcription. Sci STKE. 256:51. Review.

Wu, J
(9/2002-12/2006)

Articles on EPub

Wu J and Bresnick EH. (2007). Glucocorticoid and Growth Factor Synergism Requirement for Notch4 Chromatin Domain Activation. Mol Cell Biol. In Press.

Pal S, Wu J, Murray JK, Gellman SH, Wozniak MA, Keely PJ, Boyer ME, Gomez TM, Hasso SM, Fallon JF, and Bresnick EH (2006). An anti-angiogenic neurokinin-B/thromboxane A2 regulatory axis. J Cell Biol. 174:1047-58.

Wu J, Iwata F, Grass JA, Osborne CS, Elnitski L, Fraser P, Ohneda O, Yamamoto M, and Bresnick EH. (2005). Molecular determinants of NOTCH4 transcription in vascular endothelium. Mol Cell Biol. 25:1458-1474.

Im H.*, Grass JA* Johnson KD, Boyer ME, Wu J, and Bresnick EH. (2004). Measurement of protein-DNA interactions in vivo by chromatin immunoprecipitation. Methods Mol Biol: Signal Transduction Protocols. 284:129-146. (*co-first authors)

Grass JA, Boyer ME, Paul S, Wu J, Weiss MJ, and Bresnick EH. (2003). GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling. PNAS USA. 100:8811-8816. PMID: 12857954

Vaughan, E.M*
(9/2003-2004)

Articles on EPub

Santarius, M.L.*
(9/2004-2006)

Gonzales, M.L.**
(9/2000-4/2007)

Articles on EPub

Mellman DL, Song C, Gonzales ML, and Anderson RA. (2007). A novel PI4,5P2 regulated poly(A) polymerase associates with the mRNA polyadenylation complex. Science. In revision. 

Gonzales ML, Song C, Mellman DL, and Anderson RA. (2007). Regulation of the Star-PAP-PIP kinase complex by an associated protein kinase that is regulated by PIP2. In preparation.

Bunce MW, Gonzales ML, and Anderson RA. (2006). Stress-ING out: phosphoinositides mediate the cellular stress response. Sci STKE. 360:pe46. PMID 17090802

Gonzales ML and Anderson RA. (2006). Nuclear phosphoinositide kinases and inositol phospholipids. J Cell Biochem. 97:252-260.

Doan, A.T.**
(9/2001-4/2007 )

Articles on EPub

Doan AT and Huttenlocher A. (2007). RACK1 regulates Src activity and modulates paxillin dynamics during cell migration. Exp Cell Re. 313:2667-2679. PMID 17574549. 

Cox EA, Bennin D, Doan AT, O'Toole T, and Huttenlocher A. (2003). RACK1 regulates integrin-mediated adhesion, protrusion, and chemotactic cell migration via its Src-binding site. Mol Biol Cell. 14:658-669. PMID 12589061

Duan, H
(9/2001-4/2007)

Articles on EPub

Duan H and Jefcoate CR. (2007). The predominant cAMP-stimulated 3 x 5 kb StAR mRNA contains specific sequence elements in the extended 3'UTR that confer high basal instability. J Mol Endocrinol. 38:159-179. PMID 17242178

Zhao D, Duan H, Kim YC, and Jefcoate CR. (2005). Rodent StAR mRNA is substantially regulated by control of mRNA stability through sites in the 3'-untranslated region and through coupling to ongoing transcription. J Steroid Biochem Mol Biol. 96:155-173. PMID 16039847

Duan H and Jefcoate C. (2004). Effective StAR expression in mouse MA-10 and Y-1 cells: extensiveoverexpression does not increase basal or cAMP-induced steroidogenesis. Endocr Res. 30:769.

LeBlanc, S.E.**
(2002-2007)

Articles on EPub

LeBlanc SE, Jang SW, Ward RM, Wrabet L, and Svaren J. (2006). Direct regulation of myelin protein zero expression by the Egr2 transactivator. J Biol Chem. 281:5453-5460.

Jang SW, LeBlanc SE, Roopra A, Wrabetz L, and Svaren J. (2006). In vivo detection of Egr2 binding to target genes during peripheral nerve myelination. J Neurochem. 98:1678-1687.

LeBlanc SE, Srinivasan R, Ferri C, Mager GM, Gillian-Daniel AL, Wrabetz L, and Svaren J. (2005). Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination. J Neurochem. 93:737-748.

Shi Y, Venkataraman SL, Dodson GE, Mabb AM, LeBlanc SE, and Tibbetts RS. (2004). Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress. PNAS USA. 101:5898-5903.

Fu VX, Schwarze SR, Kenowski ML, LeBlanc SE, Svaren J, and Jarrard DF. (2004). A loss of insulin-like growth factor-2 imprinting is modulated by CCCTC-binding factor down-regulation at senescence in human epithelial cells. J Biol Chem. 279:52218-52226.

LeBlanc SE, Ward RM, and Svaren J. (2006). Dominant Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10. (Submitted to EMBO Journal)

Mabb, A.M.**
(2002-2007)

Articles on EPub

Mabb AM and Miyamoto S. (2007). SUMO and NF-kB Ties. Cell Mol Life Sci. 64:1979-1996. Review. PMID 17530464

Mabb AM, Wuerzberger-Davi SM, and Miyamoto S. (2006). PIASy mediates NEMO sumoylation and NF-kB activation in response to genotoxic stress. Nature Cell Biol. 8:986-993.

Wu Z, Mabb AM, and Miyamoto S. (2005). PIDD: a switch hitter. Cell. 123:980-982.

Shi Y, Venkataraman SL, Dodson GE, Mabb AM, LeBlanc S, and Tibbetts RS. (2004). Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress. PNAS. 101:5898-5903.

Mager, G.M.**
(2002-2007)

Articles on EPub

Srinivasan R, Mager GM, Ward RM, Mayer J, and Svaren J. (2006). NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex. J Biol Chem. 281:15129-15137.

Leblanc SE, Srinivasan R, Ferri C, Mager GM, Gillian-Daniel AL, Wrabetz L, and Svaren J. (2005). Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination. J Neurochem. 93:737-748.

Shi Y, Dodson GE, Mukhopadhyay PS, Shanware NP, Trinh AT, and Tibbetts RS. (2007). Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies. J Biol Chem. 282:9236-9243. PMID 17244605