| 8:30-9:00 am |
Registration – Coffee with Continental Breakfast (2nd Floor) |
| 9:00-9:05 |
Opening Remarks by Dr. Jeffery Walker
Chair, Symposium Committee
Professor, Department of Physiology |
| 9:05-9:10 |
Welcome by Professor George Wilding
Director of UW Comprehensive Cancer Center |
| Session Chair: |
Dr. David Wassarman, Associate Professor of Pharmacology |
| 9:10-9:35 |
Filamin A-β1 integrin complex regulates myosin-mediated collagen remodeling to tune breast epithelial cell morphogenesis in a 3D matrix
Dr. Scott Gehler
Dr. Patricia Keely
Department of Pharmacology |
| 9:40-10:05 |
ERRα—Co-Activator GRIP1 Protein-Protein Interaction:
A Target For Novel Breast Cancer Therapeutics?
Jennifer A. Lamberski
Dr. Richard A. Burgess
MCP Program/Department of Oncology |
| 10:10-10:35 |
Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling
Christine T. Ferrara
Dr. Alan Attie
Department of Cancer Biology |
| 10:40-11:05 |
Proteasome Inhibitor Resistant NF-kappaB Activity
in Multiple Myeloma
Stephanie Markovina
Dr. Shigeki Miyamoto
CMB Program/Department of Pharmacology |
| 11:05-12:00 |
Poster Session – Main Lobby
Coffee Break – 2nd Floor |
| 12:00 |
Key Note Address: Signaling Pathways Defining Metastatic Tumor Cell Behavior In Vivo
Dr. John Condeelis
Professor and Co-Chair
Department of Anatomy and Structural Biology at the
Einstein College of Medicine |
| 1:00-2:00 |
LUNCH – Main Floor Dining Room |
| Session Chair: |
Dr. Anna Huttenlocher, Associate Professor, Medical Micro |
| 2:00-2:25 |
DCR-1 Helicase Mutation Disrupts Endogenous RNAi of Sperm
Enriched Genes
Derek Pavelec
Dr. Scott G. Kennedy
MCP Program/Department of Pharmacology |
| 2:30-2:55 |
Defining Smad protein binding “hot-spots” with mutations, peptide aptamers and small molecule ligands
Michelle M. Bonar
Dr. F Michael Hoffmann
Department of Cancer Biology |
| 3:00-3:25 |
Chronic inflammation during muscle degeneration in zebrafish
Kevin B. Walters
Dr. Anna Huttenlocher
Department of Medical Microbiology and Immunology |
| 3:30-3:55 |
Nucleotide Receptor P2RX7 Mediates AP-1 Protein Expression in Monocytic Cells
Monica Gavala
Dr. Paul J. Bertics
Department of Biomolecular Chemistry |
| 4:00-4:15 |
Final Remarks - Dr. Jeff Walker and Dr. Patricia Keely |
