William Bement, Ph.D.

Professor of Zoology

wmbement@wisc.edu

Trainer in the Following Program:

  • Molecular & Cellular Pharmacology

Awards and Honors:

  • Not Available

Research Interest:

Our lab has a long-standing interest in the means by which the cytoskeleton controls cell division, wound healing, and endocytosis. We have developed several model systems that help simplify analysis of complex, cytoskeleton-dependent processes; these are described in our recent publications.

Recent Publications: Articles on PubMed

  • Woolner S, O'Brien L, Wiese C, and Bement WM. (2008). Myosin-10 and actin filaments are essential for mitotic spindle function. J Cell Biol. In press.

  • Miller AL, von Dassow G, and Bement WM. (2008). Control of the cytokinetic apparatus by flux of the Rho GTPases. Biochem Soc Trans. 36:378-380.

  • Schietroma C, Yu HY,  Wagner MC, Umbach JA, Bement WM, and Gundersen CB. (2007). A role for myosin-1E in cortical granule exocytosis in Xenopus oocytes. J Biol Chem. 282:29504-29513.

  • Yu HYand Bement WM. (2007). Multiple myosins are required to coordinate actin assembly with coat compression during compensatory endocytosis. Mol Biol Cell. 18:4096-4105.

  • Burkel BM, von Dassow G, and Bement WM. (2007). Versatile fluorescent probes for actin filaments based on the actin binding domain of utrophin. Cell Motil Cytoskel.  64:822-832.

  • Bement WM. (2007).Cytokinetic pyrotechnics. Dev Cell. 12:663-664.

  • Yu HE and Bement WM. (2007).Control of local assembly by membrane fusion-dependent mixing compartment mixing. Nature Cell Biol.  9:149-159.

  • Bement WM, Yu HE, Burkel BM, Vaughan EM, and Clark AG. (2007). Rehabilitation and the single cell. Curr Opin Cell Biol. 19:95-100.

  • Sokac AM, Schietroma C, Gundersen C, and Bement WM. (2006). Myosin-1c links assembling actin to membranes to drive compensatory endocytosis. Dev Cell. 11:629-640.

  • Bement WM, Miller AL, and von Dassow G. (2006). Rho GTPase activity zones and transient contractile arrays. Bioessays. 28:983-93.

  • Sokac AM and Bement WM. (2006). Kiss-and-coat and compartment mixing: coupling exocytosis to signal generation and local actin assembly. Mol Biol Cell. 11:629-640. PDF PMID 17084356

  • Ma C, Benink HA, Montplaisir V, Wang L, Xi Y, Zheng P-P, Bement WM, and Liu XJ. (2006). Cdc42 activation couples spindle positioning to the first polar body formation in oocyte maturation. Curr Biol. 16:214-220. PDF PMID 16431375

  • von Dassow G and Bement WM. (2005). A ring-like template for abscission. Dev Cell. 9:578-580. PDF PMID 16256733

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Scientists in the Bement Lab:

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