Dr. Erin McDearmon

 

Research Associate
with Dr. Joseph Takahashi

Department of Neurobiology and Physiology
Howard Hughes Medical Institute Northwestern University

e-mcdearmon@northwestern.edu

Graduate Education
Dr. James Ervasti, Advisor UW-Madison 1996-2001

Research Interests:

My research is aimed at understanding the regulation of the mammalian circadian rhythm by characterizing the transcriptional regulation of a group of ìclockî genes that are expressed in a variety of tissues and species.

Publications:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=McDearmon%2Bel

  • Miller BH, McDearmon EL, Panda S, Hayes KR, Zhang J, Andrews JL, Antoch MP, Walker JR, Esser KA, Hogenesch JB, and Takahashi JS. (2007). PNAS USA. 104:3342-7. PDF PMID 17360649

  • McCarthy JJ, Andrews JL, McDearmon EL, Campbell KS, Barber BK, Miller BH, Walker JR, Hogenesch JB, Takahashi JS, and Esser KA. (2007). Identification of the circadian transcriptome in adult mouse skeletal muscle. Physiol Genomics. 31:86-95.  PMID 17550994    
           
  • Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, Balannik V, McDearmon EL, Omura C, Lumayag S, Invergo BM, Glawe B, Cantrell DR, Inayat S, Olvera MA, Vessey KA, McCall MA, Maddox D, Morgans CW, Young B, Pletcher MT, Mullins RF, Troy JB, and Takahashi JS.    (2007). Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse.  Vis Neurosci. 24:111-123. PMID 17430614

  • McDearmon EL, Patel KN, Ko CH, Walisser JA, Schook AC, Chong JL, Wilsbacher LD, Song EJ, Hong HK, Bradfield CA, Takahashi JS. (2006). Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice. Science. 314:1304-1308.  PMID 17124323

  • McDearmon EL, Combs AC, Sekiguchi K, Fujiwara H, and Ervasti JM. (2006). Brain a-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11.
    FEBS Lett. 580:3381-3385. PMID 16709410

  • Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, McDearmon EL, Fenner D, Lumayag SL, Omura C, Andrews AW, Baker M, Invergo BM, Olvera MA, Heffron E, Mullins RF, Sheffield VC, Stone EM, and Takahashi JS. (2005). Generation, characterization, and molecular cloning of the Noerg-1 mutation of rhodopsin in the mouse. Vis Neurosci. 22:619-629. PMID 16332273

  • Turek FW, Joshu C, Kohsaka A, Lin E, Ivanova G, McDearmon E, Laposky A, Losee-Olson S, Easton A, Jensen DR, Eckel RH, Takahashi JS, and Bass J. (2005).  Obesity and metabolic syndrome in circadian Clock mutant mice. Science. 308:1043-1045. PMID 15845877

  • Zambon AC, McDearmon EL, Salomonis N, Vranizan KM, Johansen KL, Adey D, Takahashi JS, Schambelan M, and Conklin BR. (2003). Time- and exercise-dependent gene regulation in human skeletal muscle. Genome Biol. 4:R61. PDF PMID 14519196

  • Smirnov S, McDearmon E, Li S, Ervasti J, Tryggvason K, and Yurchenco P. (2002). Contributions of the LG Modules and Furin Processing to Laminin-2 Functions. J Biol Chem. 277:18928-18937. PDF PMID 11886875

  • McDearmon E, Combs A, and Ervasti J. (2001). Differential Vicia villosa Agglutinin Reactivity Identifies Three Distinct Dystroglycan Complexes in Skeletal Muscle. J Biol Chem. 276:35078-35086. PDF PMID 11459841

  • McDearmon E, Burwell A, Combs A, Renley B, Sdano M, and Ervasti J. (1998). Differential Heparin Sensitivity of Dystroglycan Binding to Laminins Expressed in Normal and dy/dy Mouse Skeletal Muscle. J Biol Chem. 273:24139-24144. PDF PMID 9727035
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