Dr. Tony T. Huang

Assistant Professor

Department of Biochemistry
New York University

tony.huang@med.nyu.edu

Post-doctoral Fellow with D'Andrea

Graduate Education
Dr. S. Miyamoto, Advisor at UW Madison 1998-2003

Tony's website at New York University.

Publications:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=Huang%2Btt

  • Sims AE, Spiteri E, Sims RJ 3rd, Arita AG, Lach FP, Landers T, Wurm M, Freund M, Neveling K, Hanenberg H, Auerbach AD, and Huang TT. (2007). FANCI is a second monoubiquitinated member of the Fanconi anemia pathwa”. Nat Struct Mol Biol. 14:564-567.  PMID 17460694

  • Berchtold CM, Wu ZH, Huang TT, and Miyamoto S. (2007). Calcium-dependent regula-tion of NEMO nuclear export in response to genotoxic stimuli.  Mol Cell Biol. 27:497-509. PMID 17074802

  • Huang TT and D'Andrea AD. (2006). HAUSP hunting the FOX(O).  Nat Cell Biol. 8:1043-1045.  PMID 17013413

  • Huang TT, Nijman SMB, Mirchandani KD, Galardy PJ, Cohn MA, Haas W, Gygi SP, Ploegh HL, Bernards R and D'Andrea AD. (2006). Regulation of monoubiquitinated PCNA by DUB autocleavage. Nature Cell Biology. 8:339 (#J0121677)

  • Huang TT and D'Andrea AD. (2006). Regulation of DNA repair by ubiquitylation. Nature reviews. Molecular Cell Biology. 7:323 (#J0121676)

  • Nijman SMB, Huang TT, Dirac AM G; Brummelkamp, TR; Kerkhoven, RM; D'Andrea, AD; and Bernards, R. (2005).  The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Molecular Cell. 17:331 (#J0121680)

  • Huang TT, Davis S, Wu Z, and Miyamoto S. (2003). Sequential Modification of NEMO-kB activation by genotoxic stress. Cell. 115:565-576. PDF PMID 14651848

  • Huang TT, Feinberg S, Suryanarayanan S, and Miyamoto S. (2002). The zinc-finger domain of NEMO is selectively required for NF-kB activation by ultraviolet radiation and topoisomerase inhibitors. Mol Cell Biol. 22:5813-5825. PDF PMID 12138192

  • Huang TT and Miyamoto S. (2001). Postrepression activation of NF-kB requires the amino-terminal nuclear export signal specific to IkBa. Mol Cell Biol. 21:4737-4747. PDF PMID 11416149

  • Miyamoto S, Huang TT, Wuerzberger-Davis S, Bornmann WG, Pink JJ, Tagliarino C, Kinsella TJ, and Boothman DA. (2000). Cellular and molecular responses to topoisomerase I poisons: Exploiting synergy for improved radiotherapy. Ann NY Acad Sci. 922:274-292. PMID 11193903

  • Tsukamoto T, Yoo J, Hwang SI, Guzman RC, Hirokawa Y, Chou YC, Olatunde S, Huang TT, Bera TK, Yan J, and Nandi S. (2000). Expression of MAT1/PEA15 mRNA isoforms during physiological and neoplastic changes in the mouse mammary gland. Cancer Lett. 149:105-113. PMID 10737714

  • Huang TT, Wuerzberger-Davis SM, Seufzer BJ, Shumway SD, Kurama T, Boothman DA, and Miyamoto S. (2000). NF-kB activation by camptothecin: a linkage between nuclear DNA damage and cytoplasmic signaling events. J Biol Chem. 275:9501-9509. PDF PMID 10734098

  • Huang TT, Kudo N, Yoshida M, and Miyamoto S. (2000). A nuclear export signal in the N-terminal regulatory domain of IkBa controls cytoplasmic localization of inactive NF-kB/IkBa complexes. PNAS USA. 97:1014-1019. PDF PMID 10655476

  • Tsukamoto T, Huang T, Guzman RC, Chen X, Pascual RV, Kiamura T, and Nandi S. (1999). Isolation of oncogenes from rat mammary tumors by a highly efficient retrovirus expression cloning system. Biochem Biophys Res Commun. 265:7-12. PDF PMID 10548482

  • Bera TK, Tsukamoto T, Panda DK, Huang TT, Guzman RC, Hwang SI, and Nandi S. (1998). Defective retrovirus insertion activations c-Ha-ras protooncogene in an MNU-induced rat mammary carcinoma. Biochem Biophys Res Commun. 248:835-840. PDF PMID 9704014

  • Swanson SM, Guzman RC, Tsukamoto T, Huang TT, Dougherty CD, Nandi S. (1996). N-Ethyl-N-nitrosourea induces mammary cancers in the pituitary-isografted mouse which are histologically and genotypically distinct from those induced by N-methyl-N-nitrosourea. Cancer Lett. 102:159-165. PMID 8603364
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