Dr. Brandon Burbach

Post-doctoral Fellow
with Dr. Yoji Shimizu

University of Minnesota

burba005@umn.edu

Graduate Education
Dr. Rapraeger, Advisor at UW Madison 1997-2004

Info:

Currently has an American Heart Association Postdoctoral Fellowship
Post-Doctoral Fellow (Sept. 2004 - Present)
University of Minnesota, Center for Immunology
Minnesota Craniofacial Research Training Program (MinnCResT)
Research Project:  Regulation of T cell receptor signaling and LFA-1 integrin function by adhesion and degranulaton protein (ADAP) in primary murine T-cells.
Mentor:  Yoji Shimizu, Ph.D.

Awards:
  • Minnesota Craniofacial Research Training Program, Postdoctoral Fellow.
  • September 2004 - August 2007.   (NIH Postdoctoral Fellowship)

Travel Awards:

  • American Society for Cell Biology
  • American Society for Matrix Biology

Best Poster Awards:

  • American Society for Developmental Biology (July 2002)
  • American Society for Matrix Biology (Nov 2002)

Publications:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=search&term=Burbach%2Bbj

  • Mueller KL, Thomas MS, Burbach BJ, Peterson EJ, and Shimizu Y. (2007). Links Adhesion and Degranulation-Promoting Adapter Protein (ADAP) Positively Regulates T Cell Sensitivity to Antigen and T Cell Survival. J Immunol. 179:3559-3569. PMID 17785790

  • Burbach BJ, Medeiros RB, Mueller KL, and Shimizu Y. (2007). Links T-cell receptor signaling to integrins. Immunol Rev. 218:65-81. PMID 17624944

  • Burbach BJ, Mueller K, O'Gorman W, Peterson EJ, and Shimizu Y. (2006). ADAP and SKAP55 are coordinately required for efficient antigen dependent LFA-1 function on primary naïve murine T cells.  Manuscript in preparation.

  • Medeiros RB, Burbach BJ, Mueller K, Highfill S, Peterson E, and Shimizu Y. (2006).  Association of ADAP with Carma1 controls NFkB activation in T cells. Science. 316:754-8. PDF PMID 17478723

  • Fostel LV, Dluzniewska J, Shimizu Y, Burbach BJ, and Peterson EJ. (2006). ADAP is dispensible for natural killer cell development and function. Int Immunol. 18:1305-14 PDF PMID 16775024
     
  • McQuade KJ, Beauvais DM, Burbach BJ, and Rapreager AC. (2006). Syndecan-1 regulates avB5 integrin activity in B82L fibroblasts.  J Cell Sci. 119:2445-2456. PDF PMID 16720645

  • Burbach BJ, Ji Y, and Rapraeger AC. (2004). Syndecan-1 ectodomain regulates matrix-dependent signaling in human breast carcinoma cells. Exp Cell Res. 300:234-247. PDF PMID 15383330

  • Beauvais DM, Burbach BJ and Rapraeger AC. (2004). Syndecan-1 ectodomain regulates avb3 integrin activity in human mammary carcinoma cells. J Cell Biol. 167:171-181. PDF PMID 15479743

  • Burbach BJ, Friedl A, Mundhenke CH, and Rapraeger AC. (2003). Syndecan-1 accumulates in lysosomes of poorly differentiated breast carcinoma cells. Matrix Biol. 22:163-77. PDF PMID 12782143

  • Brown LM, Burbach BJ, McKenzie BA, and Connell GJ. (1999). A Cis-acting A-U sequence element induces kinetoplastid U-insertions. J Biol Chem. 274:6295-6304. PDF PMID 10037718
ABSTRACTS/POSTERS PRESENTED AT SCIENTIFIC MEETINGS (First Author Only)

Keystone Symposium:  Lymphocyte Activation and Signaling:  Steamboat Springs, CO.  January 2006.  Characterization of ADAP functional domains required for T cell activation.

2002 - won two "best-poster" awards at national scientific meetings in 2002. These were first-author posters presented at (1) The American Society for Developmental Biology in July 2002 and (2) The American Society for Matrix Biology in November 2002.