Biomedical Engineering Courses

310 Bioinstrumentation. 3 cr. A sophomore level first course in bioinstrumentation covering clinical and research measurements. Laboratory experiments complement the lectures. P: Math 234, con reg in ECE 230, Chem 109. Open only to BME majors or cons inst.

315 Biomechanics. 3 cr. This course will provide an introduction to the mechanical behavior of biological tissues and systems. Specific topics include: structure and function of biological tissues, mechanical properties of biological tissues, and analysis of specific tissues (i.e. bone, muscle, and soft connective tissues). P: Math 234; EMA 202 or ME 240.

320 Introductory Transport Phenomena. (Crosslisted with CBE) 4 cr. Mass, momentum, and energy transport; calculation of transport coefficients; solution to problems in viscous flow, heat conduction, and diffusion; dimensional analysis; mass, momentum, and heat transfer coefficients; over-all balances; elementary applications. P: Physics 201, Math 319 or 320, CBE 250 with grade of C or better; or cons inst.

430 Biological Interactions with Materials. (Crosslisted with Phm Sci) 3 cr. This course addresses the range of materials currently being utilized for various biomedical applications, the biological systems governing biomaterial applications, analytical techniques pertinent to biomaterial evaluation, and selected major medical applications in which biomaterials play an important role. P: 1 yr of general biol or two semesters of zool, & 1 semester of organic chem, or cons inst.

461 Mathematical and Computer Modeling of Physiological Systems. (Crosslisted with ECE) 3 cr. Mathematical and computer modeling of physiological systems; principal emphasis on cardiovascular system and individual nerve cells; other topics include respiratory system and skeletal-muscle system; extensive use of "hands-on" computer modeling using Acsl. P: ECE 330 or cons inst.

462 Medical Instrumentation. (Crosslisted with ECE) 3 cr. Design and application of electrodes, biopotential amplifiers, biosensors, therapeutic devices. Medical imaging. Electrical safety. Measurement of ventilation, blood pressure and flow. Lecture and lab. P: ECE 342 or cons inst.

463 Computers in Medicine. (Crosslisted with ECE) 3 cr. Study of microprocessor-based medical instrumentation. Emphasis on real-time analysis of electrocardiograms. Labs and programming project involve design of biomedical digital signal processing algorithms. P: ECE 330, Comp Sci 302.

501 Radiological Physics and Dosimetry. (Crosslisted with Med Phys, H ONcol, Physics) 3 cr. Interactions and energy deposition by ionizing radiation in matter; concepts, quantities and units in radiological physics; principles and methods of radiation dosimetry. P: Calculus and modern physics.

505 Biofluidics. 3 cr. Introduction to blood rheology, blood flow dynamics in arteries, capillaries and veins, airflow in the lungs, and other physiological flow phenomena. Healthy and diseased states will be considered. Special topics may include ocular flow dynamics and electro-chemical-fluidics in cartilage. P: EMA 201; EMA 202 or ME 240; Physiol 335; or cons inst.

510 Introduction to Tissue Engineering. (Crosslisted with CBE) 3 cr. Overview of tissue engineering, including discussion of cell sources, cell-material interactions, tailoring biomaterials, methods of culture and characterization of engineering tissues, ethical issues, concluding with case studies of specific types of tissue engineering. Optional laboratory exercises offered throughout semester. P: BME 430 or equiv, or cons inst.

515 Therapeutic Medical Devices. 1 cr. Design of medical devices to treat pathology. Open to majors in biomedical engineering. One lecture each week. P: BME 310, BME 315, Physiol 335. Con reg in BME430.

517 Biology in Engineering Seminar. (Crosslisted with CBE, BSE) 1 cr. Current topics at the interface of biology and engineering with special emphasis on the ways in which engineers have contributed to knowledge and advances in biology. P: Jr st in engr & one college-level biol crse.

520 Stem Cell Bioengineering. (Crosslisted with CBE) 3 cr. Covers engineering approaches that are used to understand and manipulate stem cells. Concepts covered include: introduction to stem cell biology, quantitative modeling of stem cell signaling, methods to engineer the stem cell microenvironment, and the role of stem cells in tissue development and regeneration. P: Math 319 or 320, Zoology 470 or 570, Chem 343, or cons inst.

530 Medical Imaging Systems. (Crosslisted with Med Phys) 3 cr. 2D Fourier image representation, sampling, and image filtering with applications in medical imaging. Principles of operation, impulse responses, signal-to-noise, resolution and design tradeoffs in projection radiography, tomography, nuclear medicine, ultrasound, and magnetic resonance imaging. P: ECE 330 or Med Phys 473 or equiv or cons inst. Knowledge of linear signals & systems, convolution, basic probability, Id Fourier Transforms.

550 Introduction to Biological and Medical Microsystems. 3 cr. Introduces students to the field of Mems (Micro-Electro-Mechanical-Systems), as it applies to biology and medicine. Topics will cover methodology of traditional Mems devices, how they can be incorporated with biological systems, and methods for micro-structuring biological materials. P: Zool 152, BME 310, or cons inst.

560 Biochemical Engineering. (Crosslisted with CBE) 3 cr. Application of chemical engineering principles to biomedical and microbiological problems. P: CBE 426; Chem 561 or 562; Biochem 501 or equiv; or cons inst.

561 Biomolecular Engineering Laboratory. (Crosslisted with CBE) 3 cr. Brief review of physical chemistry of biological macromolecules. Theory and laboratory experiments aimed at developing skills at preparing and characterizing biological macromolecules and macromolecular assemblies. Half-semester-long laboratory project focused on design of a specific process/product involving biomolecules. P: CBE 311; Chem 561 or 562 or 565 or equiv; Biocore 303 or Biochem 501 or equiv; or cons inst.

564 Occupational Ergonomics and Biomechanics. (Crosslisted with I SY E) 3 cr. Introduces engineers how to design manufacturing and industrial operations in which people play a significant role, so that human capabilities are maximized, physical stress is minimized, and workload is optimized. Examples and topics emphasize industrial applications. P: Ind Engr 349, Grad st or cons inst.

566 Physics of Radiotherapy. (Crosslisted with Med Phys) 3 cr. Ionizing radiation use in radiation therapy to cause controlled biological effects in cancer patients. Physics of the interaction of the various radiation modalities with body-equivalent materials, and physical aspects of clinical applications; lecture and lab. P: Med Phys 501.

567 The Physics of Diagnostic Radiology. (Crosslisted with Med Phys) 3 cr. Physics of x-ray diagnostic procedures and equipment, radiation safety, general imaging considerations; lecture and lab. P: Modern physics, calculus, and Fourier analysis, or cons inst.

568 Magnetic Resonance Imaging (MRI). (Crosslisted with Med Phys) 3 cr. Physics and technology of magnetic resonance imaging (MRI), emphasizing techniques employed in medical diagnostic imaging. Major topics: physics of MR, pulse sequences, hardware, imaging techniques, artifacts, and spectroscopic localization. P: Crses in mod physics & calc, incl Fourier Anal, req. Crses in other med imaging tech e.g. Med Phys 567, & crses in signal processing, or Med Phys 573 recommended.

573 Medical Image Science: Deterministic Aspects. (Crosslisted with Med Phys) 3 cr. The conceptual and mathematical foundations of linear systems theory in medical imaging, with example demonstrations of their applications in particular medical imaging modalities. P: 1 yr each of undergrad physics & calc or cons inst.

574 Medical Image Science: Stochastic Aspects. (Crosslisted with Med Phys) 3 cr. The conceptual and mathematical foundations of probability and statistics in medical imaging, and demonstrations of the applications of these foundations in particular medical imaging modalities. P: Med Phs/BME 573 or cons inst.

575 Diagnostic Ultrasound Physics. (Crosslisted with Med Phys) 3 cr. Propagation of ultrasonic waves in biological tissues; principles of ultrasonic measuring and imaging instrumentation; design and use of currently available tools for performance evaluation of diagnostic instrumentation; biological effects of ultrasound. P: Modern physics, calculus & Fourier analysis or cons inst.

601 Special Topics in Biomedical Engineering. 1-3 cr. Topics vary. P: Grad st or cons inst.

603 Topics in Bio-Medical Engineering. (Crosslisted with ME) 1-3 cr. Various aspects of living systems of interest to the mechanical engineer, such as the mechanics of hearing and vision, cardiac and central nervous systems, artificial organs, blood flow behavior, and energy-transfer processes. P: Cons inst.

615 Tissue Mechanics. 3 cr. This course will focus on solid mechanics of prominent musculoskeletal and cardiovascular tissues. Their normal and pathological behaviors (stiffness, strength, relaxation, creep, adaptive remodeling, etc.) in response to physiolgic loading will be examined and quantified. P: BME 315 or cons inst.

619 Microscopy of Life. (Crosslisted with Physics, Anatomy, Chem, Med Phys, Phmcol-M, Radiol) 3 cr. Survey of state of the art microscopic, cellular and molecular imaging techniques, beginning with subcellular microscopy and finishing with whole animal imaging. P: 2nd semester intro physics including light & optics (e.g. 104, 202, 208) or cons inst.

662 Design and Human Disability and Aging. (Crosslisted with I SY E) 3 cr. Design of products for persons with physical, sensory or cognitive impairments is covered as well as the design of standard mass market products. Interdisciplinary teams explore specific disabilities, then design a standard mass market product in competition with each other. P: Jr st or cons inst.

699 Advanced Independent Study. 1-5 cr. Under faculty supervision. P: Cons inst.

701 Seminar in Biomedical Engineering. 0 cr. Speakers present current research, reviews of previous research, or topics of interest to biomedical engineering graduate students and faculty. P: Grad st in biomedical engineering.

702 Graduate Cooperative Education Program. 1-2 cr. Work experience that combines classroom theory with practical knowledge of operations to provide students with a background on which to develop and enhance a professional career. The work experience is tailored for MS students from within the U.S. as well as eligible international students.

762 Biomedical Instrumentation. (Crosslisted with ECE) 3 cr. Design and application of specialized biomedical instrumentation. Information retrieval techniques. Lab. P: ECE 462 or cons inst.

763 Projects in Computers in Medicine. (Crosslisted with ECE) 3 cr. Applications of digital computers to the solution of problems in clinical and research medicine. Hardware and software student projects. P: ECE 463.

764 Occupational Biomechanics. (Crosslisted with I SY E) 3 cr. Advanced study of biomechanical and physiological modeling and measurement techniques useful in the study and mitigation of physical stressors in the industrial workplace and for preventing musculoskeletal disorders in manual work. P: Ind Engr 564 or Grad st.

775 Advanced Ultrasound Physics. (Crosslisted with Med Phys, Physics) 3 cr. Foundations of acoustic wave equations, diffraction phenomena and acoustic beam formation, models for acoustic scattering from discrete structures and inhomogeneous continua, speckle statistics including speckle correlation, applications of these topics in medical imaging. P: Med Phys 575, Physics 311, 322, 325, Math 234, or cons inst.

782 Modeling Biological Systems. (Crosslisted with CBE) 3 cr. Literature survey of mathematical models in biology at the molecular and cellular levels; application of chemical kinetics and thermodynamics to biological systems; comparison of deterministic and stochastic strategies. P: Math 319 or 320 or cons inst.

783 Design of Biological Molecules. (Crosslisted with CBE) 3 cr. Introduction to the methodologies for engineering the structure and function of biological molecules, especially proteins. Students will develop an understanding for the integration of computation and experiment to address biological molecular engineering problems. P: Biocore 303 or Biochem 501 or Zoology 570; or cons inst.

790 Master's Research and Thesis. 1-9 cr. Under faculty supervision. P: Grad st; for Master's candidates only.

890 Pre-dissertation Research. 1-9 cr. Under faculty supervision. P: Grad st; for pre-dissertators only.

909 Special Topics in Bioengineering. (Crosslisted with ECE) 1-3 cr. P: Cons inst.

915 Computation and Informatics in Biology and Medicine. (Crosslisted with B M I, Biochem, Genetics, CBE, Comp Sci) 1 cr. Participants and outside speakers will discuss current research in computation and informatics in biology and medicine. This seminar is required of all Cibm program trainees. P: Cons inst.

990 Research and Thesis. 1-9 cr. Under faculty supervision. P: Dissertator status & cons inst.

999 Advanced Independent Study. 1-9 cr. Under faculty supervision. P: Cons inst.