Genetics and Medical Genetics Courses


GENETICS

466 General Genetics. (Crosslisted with Botany, Zoology) 3 cr. Genetics in eukaryotes and prokaryotes. Includes Mendelian genetics, mapping, molecular genetics, genetic engineering, cytogenetics, quantitative genetics, and population genetics. Illustrative material includes viruses, bacteria, plants, fungi, insects, and humans. P: Algebra, 1 yr chem & 1 yr biology or cons inst.

472 Molecular Evolution. (Crosslisted with Entom) 3 cr. Basic principles of molecular evolution. Lecture topics include population genetics, molecular phylogenetics, rates and patterns of evolution, genome evolution, and molecular ecology. While emphasis will be on insect model systems, examples from other groups of organisms also will be presented. P: Genetics 466 or Biocore sequence, or cons inst.

545 Genetics Laboratory. 2 cr. Students gain practical experience in classical and molecular genetic laboratory techniques using plants, animals, and fungi. Topics include complementation and linkage analysis, gene mapping, library screening, yeast and bacterial transformation, restriction analysis, PCR, sequencing, and Southern blot analysis. P: Genetics 466 or equiv.

561 Introductory Cytogenetics. (Crosslisted with Botany, Hort) 2-3 cr. Mitosis, meiosis, variations in chromosome structure and number, cytological aspects of hybridity and apomixis; chromosomes as they affect breeding behavior. P: Genetics, Botany, Zoology 466 or cons inst.

565 Human Genetics. (Crosslisted with Md Genet) 3 cr. Principles, problems, and methods of human genetics. Surveys aspects of medical genetics, biochemical genetics, molecular genetics, cytogenetics, quantitative genetics, and variation as applied to humans. P: Genet 466 or equiv or cons inst.

566 Advanced Genetics. 3 cr. Principles of classical and molecular genetic analysis taught through readings in the scientific literature. P: Genetics 466 (or equiv) & genetics major or cons inst. Required of all undergrad genetics majors.

607 Advanced Microbial Genetics. (Crosslisted with Microbio) 3 cr. Molecular genetic methods and related aspects of prokaryotic and lower eukaryotic biology, as well as critical analysis of the scientific literature. Approximately two-thirds of the course will focus on prokaryotes and one-third on lower eukaryotic microbes. P: Genetics 466 or equiv, Biochem 501 or equiv, & Grad st or cons inst.

610 Quantitative Genetics. (Crosslisted with An Sci) 3 cr. An advanced approach with emphasis on statistical foundations. Classical theory with extensions to maternal and paternal effects. Selection theory is considered in depth. P: Genetics 466 and Statistics 572 or cons inst.

612 Prokaryotic Molecular Biology. (Crosslisted with Microbio, Biochem) 3 cr. Molecular basis of bacterial physiology and genetics with emphasis on molecular mechanisms; topics include nucleic acid-protein interactions, transcription, translation, replication, recombination, regulation of gene expression. P: Bact 370 or equiv & Biochem 501 or equiv, or cons inst.

655 Biology and Genetics of Filamentous Fungi. (Crosslisted with Pl Path, Microbio, Botany, MM&I) 3-4 cr. Fungal genetics, genomics, and physiology using plant pathogenic fungi and the genetic models Aspergillus nidulans and Neurospora crassa as model systems to explore the current knowledge of fungal genetics and plant/fungal interactions. P: Cons inst; Pl Path 300 & 332 recommended; Genetics 466 or equiv; general microbiol crse.

677 Advanced Topics in Genetics. (Crosslisted with Md Genet) 1-3 cr. Contents vary; consideration of subjects not included in the curriculum. P: Cons inst or Grad st.

699 Special Problems. 1-3 cr. Advanced work not covered in regular courses. P: Cons inst and Sr st.

701 Advanced Genetics. 2 cr. Advanced Genetics is a two credit lecture course for graduate students in Genetics and related fields. The course covers, at the graduate level, five main topics, each comprising six lectures with discussion: linkage and mapping, non-Mendelian inheritance, chromosomal phenomena, mutation and screening, and meiosis. P: Grad st or cons inst. Genetics 466 or equiv.

703 Topics in Eukaryotic Regulation. (Crosslisted with Biochem) 2 cr. Design and interpretation of experiments addressing molecular mechanisms of eukaryotic regulation. For first year graduate students with firm knowledge of basic biochemistry, molecular biology and genetics. P: Biochem 612 or equiv & cons inst.

708 Methods and Logic in Genetic Analysis. (Crosslisted with Md Genet) 3 cr. Contemporary issues in genetic, developmental, cell, and molecular biology are addressed in a discussion format. Invited speakers give researech lectures and reading material is taken from the primary literature. The discussion fucuses on evaluating genetic approaches to biological problems. P: Grad st, Genetics 701 or equiv.

731 Clinical Genetics. (Crosslisted with Md Genet, Nursing) 3 cr. Clinical manifestation of human genetic disorders, practical principles of genetic counseling; for students preparing for genetic counseling and other health care professions, e.g., nursing, physician's assistant, etc., in which they will encounter patients/families with genetically determined conditions, disorders, related problems, and prevention. P: Genetics 466 or equiv; Genetics 565 & 561 or 562; or cons inst. Some knowledge of basic medical terminology essential.

770 Genetics Counseling. (Crosslisted with Md Genet) 1 cr. Necessary genetic information and mathematical techniques for genetic counseling. Topics: basic human genetics review, elementary probability, pedigree and segregation analysis, cytogenetics, empirical risks, eugenics and counseling practice. Practical aspects. P: Sr st in Med School or cons inst.

799 Practicum in Genetics Teaching. 1-3 cr. P: Grad st & cons inst.

840 Regulatory Mechanisms in Plant Development. (Crosslisted with Botany, Biochem) 3 cr. Molecular mechanisms whereby endogenous and environmental regulatory factors control development; emphasis on stimulus perception and primary events in the signal chain leading to modulated gene expression and cellular development; lecture. P: Biochem 501 or 601 & Botany 500 or Biocore 301 & 323.

875 Special Topics. 1-4 cr. Special topics of current interest to graduate students. P: Grad st and cons inst.

915 Computation and Informatics in Biology and Medicine. (Crosslisted with B M I, Biochem, BME, CBE, Comp Sci) 1 cr. Participants and outside speakers will discuss current research in computation and informatics in biology and medicine. This seminar is required of all Cibm program trainees. P: Cons inst.

951 Seminar in Animal Breeding. (Crosslisted with An Sci, Dy Sci) 0-1 cr. P: Cons inst.

957 Seminar-Plant Breeding. (Crosslisted with Hort, Agronomy) 1 cr. P: Grad st.

990 Research. 1-12 cr. P: Grad st & cons inst.

993 Seminar in Genetics. 0-1 cr. Sections deal with various aspects of genetics: Drosophila, maize, immunogenetics, developmental genetics, or other special topics. Students may enroll in two or more sections if they wish. P: Grad st & cons inst.

MEDICAL GENETICS

Return to Top

565 Human Genetics. (Crosslisted with Genetics) 3 cr. Principles, problems, and methods of human genetics. Surveys aspects of medical genetics, biochemical genetics, molecular genetics, cytogenetics, quantitative genetics, and variation as applied to humans. P: Genet 466 or equiv or cons inst.

646 Cancer Genetics. 2 cr. Provides students with a background in cancer genetics ffrom a medical, biologic, and clinical perspective. P: Enrollment in the Genetic Counseling Training Program or cons inst.

677 Advanced Topics in Genetics. (Crosslisted with Genetics) 1-3 cr. Contents vary; consideration of subjects not included in the curriculum. P: Cons inst or Grad st.

699 Independent Reading. 1-3 cr. P: Cons inst & Sr st.

707 Genetics of Development. 3 cr. A research-level analysis of the current status of the investigation of processes controlling differential gene activity and cellular behavior. The major emphasis is genetic. In successive years, the focus moves from the gene to the cell to the organism. P: Genetics 466 or equiv, Biochem 602 or equiv.

708 Methods and Logic in Genetic Analysis. (Crosslisted with Genetics) 3 cr. Contemporary issues in genetic, developmental, cell, and molecular biology are addressed in a discussion format. Invited speakers give researech lectures and reading material is taken from the primary literature. The discussion fucuses on evaluating genetic approaches to biological problems. P: Grad st, Genetics 701 or equiv.

713 Practicum in Genetics Counseling. 3 cr. Introductory practicum in genetics counseling, designed to acquaint the student with the basic practice skills required, protocols used, and professional issues in genetics counseling. Clinical experiences in a variety of specialty clinics provide opportunities for initial development of interviewing, data collection, and counseling skills. P: Enrollment in Ms Genetics Counseling Progm.

714 Practicum in Genetics Counseling. 3 cr. Second semester of the practicum in genetics counseling. Builds upon the first semester course (713) and provides additonal opportunities to develop and improve skills in interviewing, data collection, case management and counseling. P: Med Genet 713.

721 Medical Genetics. 2 cr. General genetics principles, with emphasis on human and clinical genetics. P: 1st yr st in Med Sch or cons inst.

731 Clinical Genetics. (Crosslisted with Genetics, Nursing) 3 cr. Clinical manifestation of human genetic disorders, practical principles of genetic counseling; for students preparing for genetic counseling and other health care professions, e.g., nursing, physician's assistant, etc., in which they will encounter patients/families with genetically determined conditions, disorders, related problems, and prevention. P: Genetics 466 or equiv; Genetics 565 & 561 or 562; or cons inst. Some knowledge of basic medical terminology essential.

737 Contemporary Professional Issues in Genetics Counseling. 1 cr. A series of selected basic issues and topics that are core curricular requirements specific to genetics counseling. Relevant, non-redundant topics will be scheduled over four consecutive semesters. P: Enrollment in Genetics Counseling Progm or cons inst.

739 Literature Search Strategies and Analysis in Clinical Genetics. 2 cr. Approaches to literature searching including computerized databases and information retrieval are covered. Methods are provided for the students to learn to read clinical literature critically, to recognize and assess biases and to understand the limits of currently available clinical genetics studies. P: Enrollment in Genetic Counseling Progm in Dept of Med Genetics.

742 Human Embryology, Teratology and Abnormal Development. 1 cr. Review the basic processes and events of human embryology as a frame of reference in preparation for lectures on genetic and teratogenetic disturbances of normal development, focus on the major processes of morphogenesis, focus on the timing of major events in embryogenesis. P: Enrollment in the Genetic Counseling Program.

744 Applications of Biochemical Genetics for Genetic Counselors. 2 cr. This course will introduce to the genetics counseling trainee applications of biochemical and molecular diagnostic tests in clinical practice and will review the major classes of inborn errors of metabolism. P: Enrollment in Genetic Counseling Progm in Dept of Med Genetics.

770 Genetics Counseling. (Crosslisted with Genetics) 1 cr. Necessary genetic information and mathematical techniques for genetic counseling. Topics: basic human genetics review, elementary probability, pedigree and segregation analysis, cytogenetics, empirical risks, eugenics and counseling practice. Practical aspects. P: Sr st in Med School or cons inst.

813 Advanced Practicum in Genetics Counseling. 4 cr. A two semester program of clinical experiences which explores some of the pertinent professional issues in genetics counseling. The clinical experiences consist of four eight-week rotations which provide many opportunities for trainees to work toward perfecting skills in counseling, interviewing, data collection, case coordination and ongoing follow-along of genetics families. P: Med Genet 713 & 714.

814 Advanced Practicum in Genetics Counseling. 4 cr. A two semester program of clinical experiences which explores some of the pertinent professional issues in genetics counseling. The clinical experiences consist of four eight-week rotations which provide many opportunities for trainees to work toward perfecting skills in counseling, interviewing, data collection, case coordination and ongoing follow-along of genetics families. P: Med Genet 813.

990 Research. 1-12 cr. P: Cons inst.

993 Seminar in Genetics. 0-1 cr. Sections deal with various aspects of genetics: Drosophila, maize, immunogenetics, developmental genetics, or other special topics. Students may enroll in two or more sections if they wish. P: Grad st & cons inst.

999 Independent Work. 1-3 cr. P: Cons inst.