Food Research Institute: CLA (conjugated linoleic acid) references

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References on Conjugated Linoleic Acid (CLA)
updated 19 May 2008

year of publication: | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001 | 2000 | prior to 2000 |

2007
Analytical Methods	for detection of CLA and its isomers
Effect of Diet	and other conditions on CLA levels in animals and animal products
Food, CLA content
General Articles and Reviews	If review articles can fit into one other category, e.g. Food, then they are put into that category; if they cover material that would be in more than one category, then they will be here in "General"
Physiological Effects of CLA (includes fat/protein levels, anticarcinogenic effects, etc.):	in Human Studies; in Laboratory Animals, Companion Animals (pets); in Food/Farm Animals (ruminants, swine, poultry, fish); in Cell Cultures, In Vitro Studies
Synthesis of CLA	in vitro, microbial, plant

added 6/16/08

Mihhejev K, Henno M, Ots M, Rihma E (Rihma, Eve), Elias P (Elias, Priit), Kuusik S (Kuusik, Sirje), Kart O. Effects of fat-rich oil cakes on cheese fatty acid composition, and on cheese quality. Veterinarija Ir Zootechnika 40(62):55-61 (2007).

added 5/19/08
Review

Chardigny JM, Malpuech-Brugere C. Trans and conjugated fatty acids: origins and nutritional effects. Nutr. Clin. Metab. 21(1):46-51 (2007).

Food

Lee JI, Ha YJ, Lee JR, Joo YK, Kwack SJ, Do CH. Effects of conjugated linoleic acid-triglyceride additives on quality characteristics of pressed ham. Korean J. Food Sci. Anim. Res. 27(1):8-15 (2007).
Secchiari P, Mele M, Serra A. Conjugated linoleic acid in meat and milk from ruminants: principal factors of genetic variations in food. Progress Nutr. 9(2):108-123 (2007).

Diet

Egger P, Holzer G, Segato S, Werth E, Schwienbacher F, Peratoner G, Andrighetto I, Kasal A. Effects of oilseed supplements on milk production and quality in dairy cows fed a hay-based diet. Italian J. Anim. Sci. 6(4):395-405 (2007).
Rulquin H, Hurtaud C, Lemosquet S, Peyraud JL. Quantification of the effects of energetic nutrients on fat content of cow milk. Productions Animales 20(2):163-176 (2007).
Staszak E. Fatty acid content of milk from cows fed different diets. Ann. Anim. Sci. 7(1):123-130 (2007).
Weglarz A, Makulska J, Tombarkiewicz B. Suitability of Polish Red cattle for the production of milk of high biological quality in the ecological management system. Ann. Anim. Sci. 7(2):313-320 (2007).
Wyss U, Collomb M. Influence of temporary and permanent grassland on milk fat composition. Agrarforschung 14(9):418-423 (2007).

Lab animals

Lasa A, Simon E, Churruca I, Fernandez-Quintela A, Rodriguez VM, Portillo MP. Adiposity and serum parameters in hamsters fed energy restricted diets supplemented or not with trans-10,cis-12 conjugated linoleic acid. J. Physiol. Biochem. 63(4):297-304 (2007).

2007

Analytical Methods return to top

Aldai N, Rolland DC, Kramer JKG, Dugan ER. Rapid determination of total CLA concentration in beef fat. Can. J. Anim. Sci. 87(2):181-184 (2007).
Azizian H, Kramer JKG, Winsborough S. Factors influencing the fatty acid determination in fats and oils using Fourier transform near-infrared spectroscopy. European J. Lipid Sci. Technol. 109(9):960-968 (2007).
Barrett E, Ross RP, Fitzgerald GF, Stanton C. Rapid screening method for analyzing the conjugated linoleic acid production capabilities of bacterial cultures. Appl. Environ. Microbiol. 73(7):2333–2337 (2007).
Bondia-Pons I, Molto-Puigmarti C, Castellote AI, Lopez-Sabater MC. Determination of conjugated linoleic acid in human plasma by fast gas chromatography. J. Chromatogr. A 1157(1-2):422-429 (2007).
Christie WW, Dobson G, Adlof RO. A practical guide to the isolation, analysis and identification of conjugated linoleic acid. Lipids 42(12):1073-1084 (2007).
Czauderna M, Kowalczyk J, Korniluk K, Wasowska I. Improved saponification then mild base and acid-catalyzed methylation is a useful method for quantifying fatty acids, with special emphasis on conjugated dienes. Acta Chromatographica 18:59-71 (2007).
Destaillats F, Golay PA, Joffre F, de Wispelaere M, Hug B, Giuffrida F, Fauconnot L, Dionisi F. Comparison of available analytical methods to measure trans-octadecenoic acid isomeric profile and content by gas-liquid chromatography in milk fat. J. Chromagr. A1145(1-2):222–228 (2007).
Golay PA, Dionisi F, Hug B, Giuffrida F, Destaillats F. Direct quantification of fatty acids in dairy powders with special emphasis on trans fatty acid content. Food Chem. 101(3):1115–1120 (2007).
Juaneda P, Ledoux M, Sebedio JL. Analytical methods for determination of trans fatty acid content in food. European J. Lipid Sci. Technol. 109(9):901-917 (2007).
Lamos SM, Shortreed MR, Frey BL, Belshaw PJ, Smith LM. Relative quantification of carboxylic acid metabolites by liquid chromatography - Mass spectrometry using isotopic variants of cholamine. Anal. Chem. 79(14):5143-5149 (2007).
Molto-Puigmarti C, Castellote AI, Lopez-Sabater MC. Conjugated linoleic acid determination in human milk by fast-gas chromatography. Anal. Chem. Acta 602(1):122-130 (2007).
Mosley EE, McGuire MA. Methodology for the in vivo measurement of the Delta(9)-desaturation of myristic, palmitic, and stearic acids in lactating dairy cattle. Lipids 42(10):939-945 (2007).
Muller A, Steinhart H. Recent developments in instrumental analysis for food quality. Food Chem. 102(2):436–444 (2007).
Nuernberg K, Dannenberger D, Ender K, Nuernberg G. Comparison of different methylation methods for the analysis of conjugated linoleic acid isomers by silver ion HPLC in beef lipids. J. Agric. Food Chem. 55(3):598–602 (2007).
Paillard D, McKain N, Rincon MT, Shingfield KJ, Givens DI, Wallace RJ. Quantification of ruminal Clostridium proteoclasticum by real-time PCR using a molecular beacon approach. J. Appl. Microbiol. 103(4):1251-1261 (2007).
Perez-Palacios T, Ruiz J, Antequera T. Improvement of a solid phase extraction method for separation of animal muscle phospholipid classes. Foo d Chem. 102(3):875-879 (2007).
Zabala A, Portillo MP, Navarro V, Macarulla MT, Barron LJR, Fernandez-Quintela A. Quantitative gas chromatographic method for the analysis of cis-9, trans-11 and trans-10, cis-12 isomers of the conjugated linoleic acid in liver. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 855(2):152-158 (2007).

Effects of Diet and Other Conditions on CLA in Animals and Animal Products return to top

AbuGhazaleh AA, Felton DO, Ibrahim SA. Milk conjugated linoleic acid response to fish oil and sunflower oil supplementation to dairy cows managed under two feeding systems. J. Dairy Sci. 90(10):4763-4769 (2007).
AbuGhazaleh AA, Holmes LD. Diet supplementation with fish oil and sunflower oil to increase conjugated linoleic acid levels in milk fat of partially grazing dairy cows. J. Dairy Sci. 90(6):2897–2904 (2007).
Akraim F, Nicot MC, Juaneda R, Enialbert F. Conjugated linolenic acid (CLnA), conjugated linoleic acid (CLA) and other biohydrogenation intermediates in plasma and milk fat of cows fed raw or extruded linseed. Animal 1(6):835-843 (2007).
Al-Sultan SI. Influence of feeding different concentration of fish oil on milk composition of Awasi goats. J. Anim. Vet. Adv. 6(1):57-60 (2007).
Aldai N, Najera AI, Martinez A, Celaya R, Osoro K. Correlation between carcass conformation and fat cover degree, and muscle fatty acid profile of yearling bulls depending on breed and mh-genotype. Livestock Sci. 107(2-3):199–212 (2007).
Aldai N, Najera AI, Dugan MER, Celaya R, Osoro K. Characterisation of intramuscular, intermuscular and subcutaneous adipose tissues in yearling bulls of different genetic groups. Meat Sci. 76(4):682–691 (2007).
Alfaia CMM, Castro MLF, Martins SIV, Portugal APV, Alves SPA, Fontes CMGA, Bessa RJB, Prates JAM. Effect of slaughter season on fatty acid composition, conjugated linoleic acid isomers and nutritional value of intramuscular fat in Barrosa-PDO veal. Meat Sci. 75(1):44–52 (2007).
Alfaia CPM, Castro MLF, Martins SIV, Portugal APV, Alves SPA, Fontes CMGA, Bessa RJB, Partes JAM. Influence of slaughter season and muscle type on fatty acid composition, conjugated linoleic acid isomeric distribution and nutritional quality of intramuscular fat in Arouquesa-PDO veal. Meat Sci. 76 (4): 787–795 (2007).
Apple JK, Maxwell CV, Sawyer JT, et al. Interactive effect of ractopamine and dietary fat source on quality characteristics of fresh pork bellies. J. Anim. Sci. 85(10):2682-2690 (2007).
Aurousseau B, Bauchart D, Faure X, Galot AL, Prache S, Micol D, Priolo A. Indoor fattening of lambs raised on pasture: (1) Influence of stall finishing duration on lipid classes and fatty acids in the longissimus thoracis muscle. Meat Sci. 76(2):241–252 (2007).
Aurousseau B, Bauchart D, Galot AL, Prache S, Micol D, Priolo A. Indoor fattening of lambs raised on pasture: 2. Influence of stall finishing duration on triglyceride and phospholipid fatty acids in the longissimus thoracis muscle. Meat Sci. 76(3):417–427 (2007).
Barton L, Marounek M, Kudrna V, Bures D, Zahradova R. Growth performance and fatty acid profiles of intramuscular and subcutaneous fat from Limousin and Charolais heifers fed extruded linseed. Meat Sci. 76(3):517–523 (2007).
Bas P, Berthelot V, Pottier E, Normand J . Effect of level of linseed on fatty acid composition of muscles and adipose tissues of lambs with emphasis on trans fatty acids. Meat Sci. 77(4):678-688 (2007).
Basarab JA, Mir PS, Aalhus JL, Shah MA, Baron VS, Okine EK, Robertson WM . Effect of sunflower seed supplementation on the fatty acid composition of muscle and adipose tissue of pasture-fed and feedlot finished beef. Can. J. Anim. Sci. 87(1):71–86 (2007).
Basarab JA, Aalhus JL, Shah MA, Mir PS, Baron, Dugan M, Okine EK, Robertson WM. Effect of feeding sunflower seeds on the performance, carcass characteristics, meat quality, retail stability and sensory characteristics of pasture-fed and feedlot finished beef. Can. J. Anim. Sci. 87(1):15–27 (2007).
Benchaar C, Petit HV, Berthiaume R, Ouellet DR, Chiquette J, Chouinard PY. Effects of essential oils on digestion, ruminal fermentation, rumen microbial populations, milk production, and milk composition in dairy cows fed alfalfa silage or corn silage. J. Dairy Sci. 90(2):886–897 (2007).
Bessa RJB, Alves SR, Jeronimo E, Alfaia CM, Prates JAM, Santos-Silva J. Effect of lipid supplements on ruminal biohydrogenation intermediates and muscle fatty acids in lambs. European J. Lipid Sci. Technol. 109(8):868-878 (2007).
Bobe G, Zimmerman S, Hammond EG, Freeman AE, Porter PA, Luhman CM, Beitz DC. Butter composition and texture from cows with different milk fatty acid compositions fed fish oil or roasted soybeans. J. Dairy Sci. 90(6):2596-2603 (2007).
Boeckaert C, Fievez V, Van Hecke D, Verstraete W, Boon N. Changes in rumen biohydrogenation intermediates and ciliate protozoa diversity after algae supplementation to dairy cattle. European J. Lipid Sci. Technol. 109(8):767-777 (2007).
Bu DP, Wang JQ, Dhiman TR, Liu SJ. Effectiveness of oils rich in linoleic and linolenic acids to enhance conjugated linoleic acid in milk from dairy cows. J. Dairy Sci. 90(2):998–1007 (2007).
Cabrita ARJ, Bessa RJB, Alves SP, Dewhurst RJ, Fonseca AJM. Effects of dietary protein and starch on intake, milk production, and milk fatty acid profiles of dairy cows fed corn silage-based diets. J. Dairy Sci. 90(3):1429–1439 (2007).
Capper JL, Wilkinson RG, Mackenzie AM, Sinclair LA. The effect of fish oil supplementation of pregnant and lactating ewes on milk production and lamb performance. Animal 1(6):889-898 (2007).
Castaneda-Gutierrez E, de Veth MJ, Lock AL, Dwyer DA, Murphy KD, Bauman DE. Effect of supplementation with calcium salts of fish oil on n-3 fatty acids in milk fat. J. Dairy Sci. 90(9):4149-4156 (2007).
Choi SH, Lim KW, Lee HG, Kim YJ, Song MK. Supplementation effects of C-18 : 2 or C-18 : 3 rich-oils on formations of CLA and TVA, and lipogenesis in adipose tissues of sheep. Asian-Austral. J. Anim. Sci. 20(9):1417-1423 (2007).
Corino C, Lo Fiego DP, Macchioni P, Pastorelli G, Di Glancamillo A, Domeneghini C, Rossi R. Influence of dietary conjugated linoleic acids and vitamin E on meat quality, and adipose tissue in rabbits. Meat Sci. 76(1):19–28 (2007).
Couvreur S, Hurtaud C, Marnet PG, Faverdin P, Peyraud JL. Composition of milk fat from cows selected for milk fat globule size and offered either fresh pasture or a corn silage-based diet. J. Dairy Sci.90(1):392–403 (2007).
Croissant AE, Washburn SP, Dean LL, Drake MA. Chemical properties and consumer perception of fluid milk from conventional and pasture-based production systems. J. Dairy Sci. 90(11):4942-4953 (2007).
Cruz-Hernandez C, Kramer JKG, Kennelly JJ, Glimm DR, Sorensen BM, Okine EK, Goonewardene LA, Weselake RJ. Evaluating the conjugated linoleic acid and trans 18 : 1 isomers in milk fat of dairy cows fed increasing amounts of sunflower oil and a constant level of fish oil. J. Dairy Sci. 90(8):3786-3801 (2007).
da Silva DC, Santos GT, Branco AF, Damasceno JC, Kazama R, Matsushita M, Horst JA, dos Santos WBR, Petit HV. Production performance and milk composition of dairy cows fed whole or ground flaxseed with or without monensin. J. Dairy Sci. 90(6):2928–2936 (2007).
Daly CM, Moloney AP, Monahan FJ. Lipid and colour stability of beef from grazing heifers supplemented with sunflower oil alone or with fish oil. Meat Sci. 77(4):634-642 (2007).
de Oliveira DE, de Medeiros SR, Tedeschi LO, Aroeira LJ, da Silva SC. Estimating forage intake of lactating dual-purpose cows using chromium oxide and N-alkanes as external markers. Scientia Agricola 64(2):103–110 (2007).
Dewhurst RJ, Moorby JM, Vlaeminck B, Fievez V. Apparent recovery of duodenal odd- and branched-chain fatty acids in milk of dairy cows. J. Dairy Sci. 90(4):1775–1780 (2007).
Diezma-Iglesias B, Garcia-Rebollar P, Ruiz-Altisent M, Alvarez-Carro C. Instrumental measurement of the texture of hard-boiled egg yolks enriched with different levels of conjugated linoleic acid. Spanish J. Agric. Res. 5(3):293–303 (2007).
Dikeman ME. Effects of metabolic modifiers on carcass traits and meat quality. Meat Sci. 77(1):121-135 (2007).
Doreau M, Rearte D, Portelli J, Peyraud JL. Fatty acid ruminal metabolism and digestibility in cows fed perennial ryegrass. European J. Lipid Sci. Technol. 109(8):790-798 (2007).
Dugan MER, Kramer JKG, Robertson WM, Meadus WJ, Aldai N, Rolland DC. Comparing subcutaneous adipose tissue in beef and muskox with emphasis on trans 18 : 1 and conjugated linoleic acids. Lipids 42(6):509-518 (2007).
Egger P, Holzer G, Segato S, Werth E, Schwienbacher F, Peratoner G, Andrighetto I, Kasal A. Effects of oilseed supplements on milk production and quality in dairy cows fed a hay-based diet. Italian J. Anim. Sci. 6(4):395-405 (2007).
Engel E, Ferlay A, Cornu A, Chilliard Y, Agabriel C, Bielicki G, Martin B. Relevance of isotopic and molecular biomarkers for the authentication of milk according to production zone and type of feeding of the cow. J. Agric. Food Chem. 55(22):9099-9108 (2007).
Eriksson SF, Pickova J. Fatty acids and tocopherol levels in M-Longissimus dorsi of beef cattle in Sweden - A comparison between seasonal diets. Meat Sci. 76(4):746–754 (2007).
Ferruzzi G, Casarosa L, Balestri G, Poli R, Andreotti L, Pistoia A. Milk characteristics of grazing sheep fed with different hay/concentrate ratio. Italian J. Anim. Sci. 6: 551-553 Suppl. 1 (2007).
Gabryszuk M, Czauderna M, Baranowski A, Strzalkowska N (Strzalkowska, Nina), Jozwik A (Jozwik, Artur), Krzyewski J. The effect of diet supplementation with Se, Zn and vitamin E on cholesterol, CLA and fatty acid contents of meat and liver of lambs. Anim. Sci. Papers Reports 25(1):25–33 (2007).
Gorocica-Buenfil MA, Fluharty FL, Bohn T, Schwartz SJ, Loerch SC. Effect of low vitamin A diets with high-moisture or dry corn on marbling and adipose tissue fatty acid composition of beef steers. J. Anim. Sci. 85(12):3355-3366 (2007).
Gorocica-Buenfil MA, Fluharty FL, Reynolds CK, Loerch SC. Effect of dietary vitamin A concentration and roasted soybean inclusion on marbling, adipose cellularity, and fatty acid composition of beef. J. Anim. Sci. 85(9):2230-2242 (2007).
Gorocica-Buenfil MA, Fluharty FL, Reynolds CK, Loerch SC. Effect of dietary vitamin A restriction on marbling and conjugated linoleic acid content in Holstein steers. J. Anim. Sci. 85(9):2243-2255 (2007).
Hernandez ERS, Jacome MMS, Lee RGH, et al. High conjugated linoleic acid (CLA) content in milk and dairy products using a dietary supplementation of sunflower seed in cows. Thrombogenic/atherogenic risk issues. Arch. Latino Amer. Nutr. 57(2):173-178 (2007).
Hocquette JF, Tesseraud S, Cassar-Malek I, Chilliard Y, Ortigues-Marty I. Responses to nutrients in farm animals: implications for production and quality. Animal 1(9):1297-1313 (2007).
Hurtaud C, Peyraud JL. Effects of feeding camelina (seeds or meal) on milk fatty acid composition and butter spreadability. J. Dairy Sci. 90(11):5134-5145 (2007).
Jambrenghi AC, Colonna MA, Giannico F, Cappiello G, Vonghia G. Effect of goat production systems on meat quality and Conjugated Linoleic Acid (CLA) content in suckling kids. Italian J. Anim. Sci. 6: 612-614 Suppl. 1 (2007).
Kim SC, Adesogan AT, Badinga L, Staples CR. Effects of dietary n-6 : n-3 fatty acid ratio on feed intake, digestibility, and fatty acid profiles of the ruminal contents, liver, and muscle of growing lambs. J. Anim. Sci. 85(3):706–716 (2007).
Kim SW, Mateo RD, Yin YL, Wu GY. Functional amino acids and fatty acids for enhancing production performance of sows and piglets. Asian-Australasian J. Anim. Sci. 20(2):295–306 (2007).
Lavrencic A, Levart A, Salobir J. Fatty acid composition of milk produced in organic and conventional dairy herds in Italy and Slovenia. Italian J. Anim. Sci. 6:437-439 Suppl. 1 (2007).
Lawrence RJ, Doyle JC, Elliott R, Norton BW, Loxton I. Effect of biotin supplementation on meat quality of F1 Wagyu/Black Angus feedlot steers of known genotype. Meat. Sci. 77(2):228-237 (2007).
Leite J, Lima E, Baptista J. Azorean bovine milk conjugated linoleic acid. Effect of green pasture diet, storage and processing temperature. Lait 87 (2): 167–179 (2007).
Lorenzen CL, Golden JW, Martz FA, Gruen IU, Ellersieck MR, Gerrish JR, Moore KC. Conjugated linoleic acid content of beef differs by feeding regime and muscle. Meat Sci. 75(1):159–167 (2007).
Loureco M, Van Ranst G, De Smet S, Raes K, Fievez V. Effect of grazing pastures with different botanical composition by lambs on rumen fatty acid metabolism and fatty acid pattern of longissimus muscle and subcultaneous fat. Animal 1(4):537–545 (2007).
Mantysaari P, Khalili H, Sariola J, Rantanen A. Use of barley fibre and wet distillers' solubles as feedstuffs for Ayrshire dairy cows. Anim. Feed Sci. Technol. 135(1-2):52–65 (2007).
Marounek M, Skrivanova V, Dokoupilova A, Czauderna M, Berladyn A. Meat quality and tissue fatty acid profiles in rabbits fed diets supplemented with conjugated linoleic acid. Vet. Med. 52(12):552-561 (2007).
Matsushita M, Tazinafo NM, Padre RG, Oliveira CC, Souza NE, Visentainer JV, Macedo EF, Ribas NP. Fatty acid profile of milk from Saanen goats fed a diet enriched with three vegetable oils. Small Ruminant Res. 72(2-3):127-132 (2007).
Mele M, Serra A, Conte G, Pollicardo A, Del Viva M, Secchiari P. Whole extruded linseed in the diet of dairy ewes during early lactation: effect on the fatty acid composition of milk and cheese. Italian J. Anim. Sci. 6: 560-562 Suppl. 1 (2007).
Miyazawa K, Sultana H, Hirata T, Kanda S, Itabashi H. Effect of brewer's grain on rumen fermentation, milk production and milk composition in lactating dairy cows. Anim. Sci. J. 78(5):519-526 (2007).
Moloney AP. Enrichment of omega-3 fatty acids and CLA in beef by diet modification. Irish Veterinary J. 60(3):180+ (2007).
Morand-Fehr P, Fedele V, Decandia M, Le Frileux Y . Influence of farming and feeding systems on composition and quality of goat and sheep milk. Small Ruminant Res. 68(1-2):20-34 (2007).
Moreno T, Varela A, Portela C, Perez N, Carballo JA, Montserrat L. The effect of grazing on the fatty acid profile of longissimus thoracis muscle in Galician Blond calves. Animal 1(8):1227-1235 (2007).
Morgante M, Piasentier E, Bonann A, Di Grigoli A, Molle G. Effect of the dam's feeding regimen on the meat quality of light suckling lambs. Italian J. Anim. Sci. 6: 570-572 Suppl. 1 (2007).
Moussavi ARH, Gilbert RO, Overton TR, Bauman DE, Butler WR. Effects of feeding fish meal and n-3 fatty acids on ovarian and uterine responses in early lactating dairy cows. J. Dairy Sci. 90(1):145–154 (2007).
Neves CA, Santos GT, Matsushita M, Alves EM, Oliveira RL, Branco AF, Silva DC, Furlan AC, Petit HV. Intake, whole tract digestibility, milk production, and milk composition of Holstein cows fed extruded soybeans treated with or without lignosulfonate. Anim. Feed Sci. Technol. 134(1-2):32–44 (2007).
Noci F, Monahan FJ, Scollan ND, Moloney AP. The fatty acid composition of muscle and adipose tissue of steers offered unwilted or wilted grass silage supplemented with sunflower oil and fishoil. Brit. J. Nutr. 97(3):502–513 (2007).
Noci F, French P, Monahan FJ, Moloney AP. The fatty acid composition of muscle fat and subcutaneous adipose tissue of grazing heifers supplemented with plant oil-enriched concentrates. J. Anim. Sci. 85(4):1062–1073 (2007).
Nudda A, Mereu A, Fancellu S, Cappio-Borlino A. Meta-analysis of nutritional effects on conjugated linoleic acid (CLA) in milk fat of dairy cows. Italian J. Anim. Sci. 6:330–332 Suppl. 1 (2007).
Odongo NE, Or-Rashid MM, Kebreab E, France J, McBride BW. Effect of supplementing myristic acid in dairy cow rations on ruminal methanogenesis and fatty acid profile in milk. J. Dairy Sci. 90(4):1851–1858 (2007).
Odongo NE, Or-Rashid MM, Bagg R, Vessie G, Dick P, Kebreab E, France J, McBride BW. Long-term effects of feeding monensin on milk fatty acid composition in lactating dairy cows. J. Dairy Sci. 90(11):5126-5133 (2007).
Osorio MT, Zumalacarregui JM, Figueira A, Mateo J. Fatty acid composition in subcutaneous, intermuscular and intramuscular fat deposits of suckling lamb meat: Effect of milk source. Small Ruminant Res. 73(1-3):127-134 (2007).
Padre RD, Aricetti JA, Gomes STM, de Goes RHDB, Moreira FB, do Prado IN, Visentainer JV , de Souza NE, Matsushita M. Analysis of fatty acids in Longissimus muscle of steers of different genetic breeds finished in pasture systems. Livestock Sci. 110(1-2):57-63 (2007).
Palander S, Griinari M, Hagg P, Nasi M. New approaches to enrich conjugated linoleic acid in eggs: dietary vaccenic acid and purified cis-9, trans-11 conjugated linoleic acid isomer. Arch. Geflugelkunde 71(6):278-280 (2007).
Paschoal JJ, Zanetti MA, Del Claro GR, de Melo MP, Pugine SP, Cunha JA. Fatty acid profile and oxidative stability of milk from Holstein cows fed with extruded soybean and organic selenium. Pesquisa Agropecuaria Brasileira 42(12):1793-1799 (2007).
Pavan E, Duckettt SK. Corn oil supplementation to steers grazing endophyte-free tall fescue. II. Effects on longissimus muscle and subcutaneous adipose fatty acid composition and stearoyl-CoA desaturase activity and expression. J. Anim. Sci. 85(7):1731–1740 (2007).
Petit HV, Palin MF, Doepel L. Hepatic lipid metabolism in transition dairy cows fed flaxseed. J. Dairy Sci. 90(10):4780-4792 (2007).
Pezzi P, Giammarco M, Vignola G, Brogna N. Effects of extruded linseed dietary supplementation on milk yield, milk quality and lipid metabolism of dairy cows. Italian J. Anim. Sci. 6:333–335 Suppl. 1 (2007).
Phillip LE, Oresanya TF, St Jacques J. Fatty acid profile, carcass traits and growth rate of red deer fed diets varying in the ratio of concentrate: dried and pelleted roughage, and raised for venison production. Small Ruminant Res. 71(1-3):215-221 (2007).
Prandini A, Sigolo S, Tansini G, Brogna N, Piva G. Different level of conjugated linoleic acid (CLA) in dairy products from Italy. J. Food Composition Anal. 20(6):472–479 (2007).
Rulquin H, Hurtaud C, Lemosquet S, Peyraud JL. Quantification of the effects of energetic nutrients on fat content of cow milk. Productions Animales 20(2):163-176 (2007).
Sampelayo MRS, Chilliard Y, Schmidely P, Boza J. Influence of type of diet on the fat constituents of goat and sheep milk. Small Ruminant Res. 68(1-2):42-63 (2007).
Santillo A, Quinto M, Dentico M, Muscio A, Sevi A, Albenzio M. Rennet paste from lambs fed a milk substitute supplemented with Lactobacillus acidophilus: Effects on lipolysis in ovine cheese. J. Dairy Sci. 90(7):3134–3142 (2007).
Scerra M, Caparra P, Foti F, Galofaro V, Sinatra MC, Scerra V. Influence of ewe feeding systems on fatty acid composition of suckling lambs. Meat Sci. 76(3):390-394 (2007).
Schoene F, Kirchheim U, Bergmann H, Rieger G, Jahreis G, Kraft A, Leiterer M, Breitschuh G . Quality of the meat of bullocks - 3. Nutrition relevant constituents - Main nutrients, energy, fatty acids and trace elements depending on breed and meat cut. Fleischwirtschaft 87(3):129–135 (2007).
Schroeder GF, Gagliostro GA. Partial replacement of corn grain with calcium salts of fatty acid in the concentrate fed to grazing primiparous and multiparous dairy cows. New Zealand J. Agric. Res. 50 (4):437-449 (2007).
Shen XZ, Nuernberg K, Nuernberg G, Zhao R, Scollan N, Ender K, Dannenberger D. Vaccenic acid and cis-9,trans-11 CLA in the rumen and different tissues of pasture- and concentrate-fed beef cattle. Lipids 42(12):1093-1103 (2007).
Sinclair LA. Nutritional manipulation of the fatty acid composition of sheep meat: a review. J. Agric. Sci. 145:419-434 Part 5 (2007).
Staszak E. Fatty acid content of milk from cows fed different diets. Ann. Anim. Sci. 7(1):123-130 (2007).
Talpur FN, Bhanger MI, Khuhawar MY. Intramuscular fatty acid profile of longissimus dorsi and semitendinosus muscle from Kundi steers fed on pasture with cottonseed cake supplement. Internat. J. Food Sci. Technol. 42(8):1007-1011 (2007).
Troegeler-Meynadier A, Nicot MC, Enjalbert F. Effects of fat source and dietary sodium bicarbonate plus straw on the conjugated linoleic acid content of milk of dairy cows. Arch. Anim. Nutr. 61(5):406-415 (2007).
Tyagi AK, Kewalramani N, Dhiman TR, Kaur H, Singhal KK, Kanwajia SK. Enhancement of the conjugated linoleic acid content of buffalo milk and milk products through green fodder feeding. Anim. Feed Sci. Technol. 133(3–4):351–358 (2007).
Van Dorland HA, Wettstein HR, Aeschlimann G, Leuenberger H, Kreuzer M. Preference of dairy cows for ryegrass, white clover and red clover, and its effects on nutrient supply and milk quality. Arch. Anim. Nutr. 61(5):371-389 (2007).
Vanhatalo A, Kuoppala K, Toivonen V, Shingfield KJ. Effects of forage species and stage of maturity on bovine milk fatty acid composition. European J. Lipid Sci. Technol. 109(8):856-867 (2007).
Varadyova Z, Kisidayova S, Siroka P, Jalc D. Fatty acid profiles of rumen fluid from sheep fed diets supplemented with various oils and effect on the rumen ciliate population. Czech J. Anim. Sci. 52(11):399-406 (2007).
Vasta V, Pennisi P, Lanza M, Barbagallo D, Bella M, Priolo A. Intramuscular fatty acid composition of lambs given a tanniniferous diet with or without polyethylene glycol supplementation. Meat Sci. 76(4):739–745 (2007).
Weglarz A, Makulska J, Tombarkiewicz B. Suitability of Polish Red cattle for the production of milk of high biological quality in the ecological management system. Ann. Anim. Sci. 7(2):313-320 (2007).
Wistuba TJ, Kegley EB, Apple JK, Rule DC. Feeding feedlot steers fish oil alters, the fatty acid composition of adipose and muscle tissue. Meat Sci. 77(2):196-203 (2007).
Wyss U, Collomb M. Influence of temporary and permanent grassland on milk fat composition. Agrarforschung 14(9):418-423 (2007).

Food, CLA levels in return to top

Addis M, Cabiddu A, Decandia M, Fiori M, Spada S, Bulleddu C, Cammelli R, Caria A, Lai V , Lutzoni G, Natale A, Oppia P, Pintus C, Spiga A, Piredda G, Porqueddu C, Molle G. A survey on the milk fatty acid composition of forty dairy sheep flocks in Sardinia. Italian J. Anim. Sci. 6: 532–534 Suppl. 1 (2007).
Akalin AS, Tokusoglu O, Gonc S, Aycan S. Occurrence of conjugated linoleic acid in probiotic yoghurts supplemented with fructooligosaccharide. Internat. Dairy J. 17(9):1089-1095 (2007).
Al-Ismail KM, Herzallah SM, Humied MA. Effect of processing and storage of Jameed on conjugated linoleic acid content and fat and cholesterol oxidation. Food Sci. Technol. 40(3):454-459 (2007).
Baublits RT, Pohlman FW, Brown AH, Johnson ZB, Proctor A, Sawyer J, Dias-Morse P, Galloway DL . Injection of conjugated linoleic acid into beef strip loins. Meat Sci. 75(1):84–93 (2007).
Bisig W, Eberhard P, Collomb M, Rehberger B. Influence of processing on the fatty acid composition and the content of conjugated linoleic acid in organic and conventional dairy products - a review. Lait 87(1):1–19 (2007).
Coakley M, Barrett E, Murphy JJ, Ross RP, Devery R, Stanton C. Cheese manufacture with milk with elevated conjugated linoleic acid levels caused by dietary manipulation. J. Dairy Sci. 90(6):2919–2927 (2007).
Considine T, Patel HA, Singh H, Creamer LK. Influence of binding conjugated linoleic acid and myristic acid on the heat- and high-pressure-induced unfolding and aggregation of beta-lactoglobulin B. Food Chem. 102(4):1270–1280 (2007).
Gabryszuk M, Strzalkowska N, Krzyzewski J. Effects of Pre- and post-partum injections of Se, Zn and vitamin E on the concentration of cholesterol, CLA isomers and fatty acids in ovine milk. Anim. Sci. Papers Reports 25(2):87-95 (2007).
Gong YS, Weber PF, Richards MP. Characterizing quality of rendered duck fat compared to other fats and oils. J. Food Qual. 30(2):169–186 (2007).
Grashorn MA. Functionality of poultry meat. J. Appl. Poultry Res. 16(1):99-106 (2007).
Hamam F, Shahidi F. Enzymatic incorporation of selected long-chain fatty acids into triolein. J. Amer. Oil Chem. Soc. 84(6):533–541 (2007).
Jain VP, Proctor A. Production of conjugated linoleic acid-rich potato chips. J. Food Sci. 72(1):S75-S78 (2007).
Karabulut I. Fatty acid composition of frequently consumed foods in Turkey with special emphasis on trans fatty acids. Internat. J. Food Sci. Nutr. 58(8):619-628 (2007).
Khanal RC, Dhiman TR. Status of milk fat conjugated linoleic acid (CLA) in selected commercial dairies. Asian-Australasian J. Anim. Sci. 20(10):1525-1538 (2007).
Kinami T, Horii N, Narayan B, Arato S, Hosokawa M, Miyashita K, Negishi H, Ikuina J, Noda R, Shirasawa S. Occurrence of conjugated linolenic acids in purified soybean oil. J. Am. Chem. Soc. 84(1):23–29 (2007).
Laloux L, du Chaffaut L, Razanamahefa L, Lafay L. Trans fatty acid content of foods and intake levels in France. European J. Lipid Sci. Technol. 109(9):918-929 (2007).
Lee JI, Ha YJ, Lee JR, Joo YK, Kwack SJ, Do CH. Effects of conjugated linoleic acid-triglyceride additives on quality characteristics of pressed ham. Korean J. Food Sci. Anim. Res. 27(1):8-15 (2007).
Luna P, Juarez M, de la Fuente MA. Conjugated linoleic acid content and isomer distribution during ripening in three varieties of cheeses protected with designation of origin. Food Chem. 103(4):1465–1472 (2007).
Martins SV, Lopes PA, Alfaia CM, Ribeiro VS, Guerreiro TV, Fontes CMGA, Castro MF, Soveral G, Prates JAM. Contents of conjugated linoleic acid isomers in ruminant-derived foods and estimation of their contribution to daily intake in Portugal. Brit. J. Nutr. 98(6)1206-1213 (2007).
Mele M, Conte G, Castiglioni B, Chessa S, Macciotta NPP, Serra A, Buccioni A, Pagnacco G, Secchiari P. Stearoyl-Coenzyme A desaturase gene polymorphism and milk fatty acid composition in Italian Holsteins. J. Dairy Sci. 90(9):4458-4465 (2007).
Mihhejev K, Henno M, Ots M, Rihma E (Rihma, Eve), Elias P (Elias, Priit), Kuusik S (Kuusik, Sirje), Kart O. Effects of fat-rich oil cakes on cheese fatty acid composition, and on cheese quality. Veterinarija Ir Zootechnika 40(62):55-61 (2007).
Moate PJ, Chalupa W, Boston RC, et al. Milk fatty acids. I. Variation in the concentration of individual fatty acids in bovine milk. J. Dairy Sci. 90(10):4730-4739 (2007).
Pakdeechanuan P, Intarapichet KO, Tongta S. Effect of extrusion parameters on conjugated linoleic acids of corn extrudates. J. Agric. Food Chem. 55(4):1463–1468 (2007).
Rodriguez-Alcala LM, Fontecha J. Hot topic: Fatty acid and conjugated linoleic acid (CLA) isomer composition of commercial CLA-fortified dairy products: Evaluation after processing and storage. J. Dairy Sci. 90(5):2083–2090 (2007).
Santercole V, Mazzette R, De Santis EPL, Banni S (Banni, Sebastiano), Goonewardene L (Goonewardene, Laki), Kramer JKG. Total lipids of sarda sheep meat that include the fatty acid and alkenyl composition and the CLA and Trans-18 : 1 isomers. Lipids 42(4):361-382 (2007).
Secchiari P, Mele M, Serra A. Conjugated linoleic acid in meat and milk from ruminants: principal factors of genetic variations in food. Progress Nutr. 9(2):108-123 (2007).
Shingfield KJ, Ahvenjarvi S, Toivonen V, Vanhatalo A, Huhtanen P. Transfer of absorbed cis-9, trans-11 conjugated linoleic acid into milk is biologically more efficient than endogenous synthesis from absorbed vaccenic acid in lactating cows. J. Nutr. 137(5):1154–1160 (2007).
Tokusoglu O, Durucasu I, Akalin AS, Serin E, Aksit S. Fatty acid and, conjugated linoleic acid profiles of infant formulas through direct transesterification of acyl lipids. Italian J. Food Sci. 19(4):477-484 (2007).
Van Nieuwenhove CP, Oliszewski R, Gonzalez SN, Chaia ABP. Influence of bacteria used as adjunct culture and sunflower oil addition on conjugated linoleic acid content in buffalo cheese. Food Res. Internat. 40(5):559–564 (2007).
Varricchio ML, Di Francia A, Masucci F, Romano R (Romano, R.), Proto V. Fatty acid composition of Mediterranean buffalo milk fat. Italian J. Anim. Sci. 6:509–511 Suppl. 1 (2007).
Zhang W, Kakuda Y, Hill AR. Conjugated linoleic acid (CLA) in processed cheese. Milk Sci. Internat. 62(2):174-178 (2007).

General Articles and Reviews return to top

Alexander LJ, MacNeil MD, Geary TW, Snelling WM, Rule DC, Scanga JA. Quantitative trait loci with additive effects on palatability and fatty acid composition of meat in a Wagyu-Limousin F-2 population. Anim. Genetics 38(5):506-513 (2007).
Alfaia CMM, Ribeiro PJLC, Trigo MJP, Alfaia AJI, Castro MLF, Fontes CMGA, Bessa RJB, Prates JAM. Irradiation effect on fatty acid composition and conjugated linoleic acid isomers in frozen lamb meat. Meat Sci. 77(4):689-695 (2007).
Chardigny JM, Malpuech-Brugere C. Trans and conjugated fatty acids: origins and nutritional effects. Nutr. Clin. Metab. 21(1):46-51 (2007).
Chilliard Y, Glasser F, Ferlay A, Bernard L, Rouel J, Doreau M. Diet, rumen biohydrogenation and nutritional quality of cow and goat milk fat. (Review.) European J. Lipid Sci. Technol. 109(8):828-855 (2007).
Combe N, Clouet P, Chardigny JM, Lagarde M, Leger CL. Trans fatty acids, conjugated linoleic acids, and cardiovascular diseases. European J. Lipid Sci. Technol. 109(9):945-953 (2007).
Gerber M, Razanamahefa L, Bougnoux P. Trans fatty acids and cancers: AFSSA recommendations. European J. Lipid Sci. Technol. 109(9):954-959 (2007).
Glasser F, Doreau M, Ferlay A, Loor JJ, Chilliard Y. Milk fatty acids: Mammary synthesis could limit transfer from duodenum in cows. European J. Lipid Sci. Technol. 109(8):817-827 (2007).
Hur SJ, Park Y. Effect of conjugated linoleic acid on bone formation and rheumatoid arthritis. (Review.) European J. Pharmacol. 568(1-3):16-24 (2007).
Kelley NS, Hubbard NE, Erickson KL. Conjugated linoleic acid isomers and cancer. J. Nutr. 137(12):2599-2607 (2007).
Kgwatalala PM, Ibeagha-Awemu EM, Hayes JF, Zhao X. Single nucleotide polymorphisms in the open reading frame of the stearoyl-CoA desaturase gene and resulting genetic variants in Canadian Holstein and Jersey cows. DNA Sequence 18(5):357-362 (2007).
Lee SR, Jeon BT, Kim SJ, Kim MH, Lee SM, Moon SH. Effects of antler development stage on fatty acid, vitamin and GAGS contents of velvet antler in spotted deer (Cervus nippon). Asian-Australasian J. Anim. Sci. 20(10):1546-1550 (2007).
Leger CL, Razanamahefa L, Margaritis I. Health risks and benefits of trans fatty acids including conjugated fatty acids in food - Synopsis of the AFSSA report and recommendations. European J. Lipid Sci. Technol. 109(9):887-890 (2007).
Luna P, de la Fuente MA, Salvador D, Marquez-Ruiz G. Differences in oxidation kinetics between conjugated and non-conjugated methyl linoleate. Lipids 42(12):1085-1092 (2007).
Nagpal R, Yadav H, Puniya AK, Singh K, Jain S, Marotta F. Conjugated linoleic acid: Sources, synthesis and potential health benefits - An overview. Current Topics Nutraceutical Res. 5(2-3):55-65 (2007).
Ouignard-Boulange A, Clouet P, Schmitt B. Effects of dietary conjugated linoleic acids in the control of adiposity and obesity-related disorders. European J. Lipid Sci. Technol. 109(9):935-944 (2007).
Park Y, Pariza MW. Mechanisms of body fat modulation by conjugated linoleic acid (CLA). (Review) Food Res. Internat. 40:311–323 (2007).
Ren Y, Wang GW, Huang JL. Preparation of liquid-core nanocapsules from poly[(ethylene oxide)-co-glycidol] with multiple hydrophobic linoleates at an oil-water interface and its encapsulation of pyrene. Biomacromolecules 8(6):1873-1880 (2007).
Sauer LA, Blask DE, Dauchy RT. Dietary factors and growth and metabolism in experimental tumors. J. Nutr. Biochem. 18(10):637-649 (2007).
Schennink A, Stoop WM, Visker MHPW, Heck JML, Bovenhuis H, van der Poel JJ, van Valenberg HJF, van Arendonk JAM. DGAT1 underlies large genetic variation in milk-fat composition of dairy cows. Anim. Genetics 38(5):467-473 (2007).
Shingfield KJ, Griinari JM. Role of biohydrogenation intermediates in milk fat depression. (Review.) European J. Lipid Sci. Technol. 109(8):799-816 (2007).
Silveira MB, Carraro R, Monereo S, Tebar J. Conjugated linoleic acid (CLA) and obesity. Public Health Nutr. 10(10A):1181-1186 Sp. Iss. SI (2007).
Zivkovic AM, German JB, Sanyal AJ. Comparative review of diets for the metabolic syndrome: implications for nonalcoholic fatty liver disease. Amer. J. Clin. Nutr. 86(2):285-300 (2007).

Physiological Effects of CLA in Humans return to top

Attar-Bashi NM, Weisinger RS, Begg DP, Li D, Sinclair AJ. Failure of conjugated linoleic acid supplementation to enhance biosynthesis of docosahexaenoic acid from alpha-linolenic acid in healthy human volunteers. Prostaglandins Leukotrienes Essential Fatty Acids 76(3):121–130 (2007).
Chouinard LE, Schoeller DA, Watras AC, et al. Bioelectrical impedance vs. four-compartment model to assess body fat change in overweight adults. Obesity 15(1):85-92 (2007).
Close RN, Schoeller DA, Watras AC, Nora EH. Conjugated linoleic acid supplementation alters the 6-mo change in fat oxidation during sleep. Amer. J. Clin. Nutr. 86(3):797-804 (2007).
Gaullier JM, Halse J, Hoivik HO, Hoye K, Syvertsen C, Nurminiemi M, Hassfeld C, Einerhand A, O'Shea M, Gudmundsen O. Six months supplementation with conjugated linoleic acid induces regional-specific fat mass decreases in overweight and obese. Brit. J. Nutr. 97(3):550–560 (2007).
Hasin A, Griinari JM, Williams JE, Shahin AM, McGuire MA, McGuire MK. Consumption of c9,t11-18 : 2 or t10,c12-18 : 2 enriched dietary supplements does not influence milk macronutrients in healthy, lactating women. Lipids 42(9):835-843 (2007).
Haug A, Hostmark AT, Harstad OM. Bovine milk in human nutrition - a review. Lipids Health Disease 6:Art. No. 25 (SEP 25 2007).
Katzman MA, Jacobs L, Marcus M, Vermani M, Logan AC. Weight gain and psychiatric treatment: is there as role for green tea and conjugated linoleic acid? Lipids Health Dis. 6:14 (May) (2007).
Kuhnt K, Kraft J, Vogelsang H,Eder K, Kratzsch J, Jahreis G. Dietary supplementation with trans-11-and trans-12-18 : 1 increases cis-9, trans-11-conjugated linoleic acid in human immune cells, but without effects on biomarkers of immune function and inflammation. Brit. J. Nutr. 97(6):1196–1205 (2007).
Lambert EV, Goedecke JH, Bluett K, Heggie K, Claassen A, Rae DE, West S, Dugas J, Dugas L, Meltzer S, Charlton K, Mohede I. Conjugated linoleic acid versus high-oleic acid sunflower oil: effects on energy metabolism, glucose tolerance, blood lipids, appetite and body composition in regularly exercising individuals. Brit. J. Nutr. 97(5):1001–1011 (2007).
Laso N, Brugue E, Vidal J, Ros E, Arnaiz JA, Carne X, Vidal S, Mas S, Deulofeu R, Lafuente A. Effects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome components. Brit. J. Nutr. 98(4):860-867 (2007).
Liguori A, D'Armiento FP, Palagiano A, Balestrieri ML, Williams-Ignarro S, de Nigris F, Lerman LO, D'Amora M, Rienzo M, Fiorito C, Ignarro LJ, Palinski W, Napoli C. Effect of gestational hypercholesterolaemia on omental vasoreactivity, placental enzyme activity and transplacental passage of normal and oxidised fatty acids. BJOG J. Ob. Gyn. 114(12):1547-1556 (2007).
Luna P, Juarez M, de la Fuente MA. Fatty acid and conjugated linoleic acid isomer profiles in human milk fat. European J. Lipid Sci. Technol. 109(12):1160-1166 (2007).
Mosley SA, Shahin AM, Williams J, McGuire MA, McGuire MK. Supplemental conjugated linoleic acid consumption does not influence milk macronutrient contents in all healthy lactating women. Lipids 42(8):723-729 (2007).
Mullen A, Moloney F, Nugent AP, Doyle L, Cashman KD, Roche HM. Conjugated linoleic acid supplementation reduces peripheral blood mononuclear cell interleukin-2 production in healthy middle-aged males. J. Nutr. Biochem. 18(10):658-666 (2007).
Muller A, Keller U, Seliger G, Barthel C, Steinhart H, Eder K. Concentrations of conjugated linoleic acids in neonatal blood in relationship to those in maternal blood. Prostaglandins Leukotrienes Essential Fatty Acids 76(4):213–219 (2007).
Nazare JA, de la Perriere AB, Bonnet F, Desage M, Peyrat J, Maitrepierre C, Louche-Pelissier C, Bruzeau J, Goudable J, Lassel T, Vidal H, Laville M. Daily intake of conjugated linoleic acid-enriched yoghurts: effects on energy metabolism and adipose tissue gene expression in healthy subjects. Brit. J. Nutr. 97(2):273-280 (2007).
Rist L, Mueller A, Barthel C, Snijders B, Jansen M, Simoez-Wust AP, Huber M, Kummeling I, von Mandach U, Steinhart H, Thijs C. Influence of organic diet on the amount of conjugated linoleic acids in breast milk of lactating women in the Netherlands. Brit. J. Nutr. 97(4):735–743 (2007).
Steck SE, Chalecki AM, Miller P, Conway J, Austin GL, Hardin JW, Albright CD, Thuillier P. Conjugated linoleic acid supplementation for twelve weeks increases lean body mass in obese humans. J. Nutr. 137(5):1188–1193 (2007).
Syvertsen C, Halse J, Hoivik HO, Gaullier JM, Nurminiemi M, Kristiansen K, Einerhand A , O'Shea M, Gudmundsen O. The effect of 6 months supplementation with conjugated linoleic acid on insulin resistance in overweight and obese. Internat. J. Obesity 31(7):1148–1154 (2007).
Tarnopolsky M, Zimmer A, Paikin J, Safdar A, Aboud A, Pearce E, Roy B, Doherty T. Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults. PLOS Clin. Trials 2(10): doi:10.1371/journal.pone.0000991 (OCT 3 2007).
Thrush AB, Chabowski A, Heigenhauser GJ, McBride BW, Or-Rashid M, Dyck DJ. Conjugated linoleic acid increases skeletal muscle ceramide content and decreases insulin sensitivity in overweight, non-diabetic humans. Appl. Physiol. Nutr. Metab. 32(3):372–382 (2007).
Watras AC, Buchholz AC, Close RN, Zhang Z, Schoeller DA. The role of conjugated linoleic acid in reducing body fat and preventing holiday weight gain. Internat. J. Obesity 31(3):481–487 (2007).
Whigham LD, Watras AC, Schoeller DA. Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans. Amer. J. Clin. Nutr. 85(5):1203–1211 (2007).

Physiological Effects of CLA in Animals: Laboratory Animals, Companion Animals return to top

Abdullah MM, Xu ZY, Pierce GN, Moghadasian MH. The effects of simultaneous administration of dietary conjugated linoleic acid and telmisartan on cardiovascular risks in rats. Lipids 42(9):855-864 (2007).
Andreoli MF, Scalerandi MV, Borel IM, Bernal CA. Effects of CLA at different dietary fat levels on the nutritional status of rats during protein repletion. Nutrition 23(11-12):827-835 (2007).
Bauchart D, Roy A, Lorenz S, Chardigny JM, Ferlay A, Gruffat D, Sebedio JL, Chilliard Y, Durand D. Butters varying in trans 18 : 1 and cis-9,trans-11 conjugated linoleic acid modify plasma lipoproteins in the hypercholesterolemic rabbit. Lipids 42(2):123–133 (2007).
Belury MA, Kavanaugh CJ, Liu KL. Conjugated linoleic acid modulates phorbol ester-induced PPAR-delta and K-FABP mRNA expression in mouse skin. Nutr. Res. 27(1):48–55 (2007).
Bergamo P, Maurano F, Rossi M. Phase 2 enzyme induction by conjugated linoleic acid improves lupus-associated oxidative stress. Free Rad. Biol. Med. 43(1):71–79 (2007).
Butz DE, Li G, Huebner SM, Cook ME. A mechanistic approach to understanding conjugated linoleic acid's role in inflammation using murine models of rheumatoid arthritis. Am. J. Physiol. Reg. Integrative Comp. Physiol. 293(2):R669-R676 (2007).
Cao ZP, Wang F, Xiang XS, Cao R, Zhang WB, Gao SB. Intracerebroventricular administration of conjugated linoleic acid (CLA) inhibits food intake by decreasing gene expression of NPY and AgRP. Neurosci. Lett. 418(3):217-221 (2007).
Choi JS, Koh IU, Jung MH, Song J. Effects of three different conjugated linoleic acid preparations on insulin signalling, fat oxidation and mitochondrial function in rats fed a high-fat diet. Brit. J. Nutr. 98(2):264-275 (2007).
Czauderna M, Kowalczyk J, Korniluk K. Effect of dietary conjugated linoleic acid and selenized yeast on the concentration of fatty acids and minerals in rats. Arch. Anim. Nutr. 61(2):135–150 (2007).
Czauderna M, Kowalczyk J, Korniluk K, Niedzwiedzka KM. Comparison of the influence of different chemical forms of selenium and the profiles of CLA isomers in the diet on the fatty acid and amino acid contents in the liver and femoral muscles of rats. J. Anim. Feed Sci. 16(4):678-695 (2007).
Di Felice V, Macaluso F, Montalbano A, Gammazza AM, Palumbo D, Angelone T, Bellafiore M, Farina F. Effects of conjugated linoleic acid and endurance training on peripheral blood and bone marrow of trained mice. J. Strength Conditioning Res. 21(1):193-198 (2007).
Dikeman ME. Effects of metabolic modifiers on carcass traits and meat quality. Meat Sci. 77(1):121-135 (2007).
Hayashi AA, de Medeiros SR, Carvalho MH, Lanna DPD. Conjugated linoleic acid (CLA) effects on pups growth, milk composition and lipogenic enzymes in lactating rats. J. Dairy Res. 74(2):160-166 (2007).
Hwang DM, Kundu JK, Shin JW, Lee JC, Lee HJ, Surh YJ. cis-9,trans-11-conjugated linoleic acid down-regulates phorbol ester-induced NF-kappa B activation and subsequent COX-2 expression in hairless mouse skin by targeting I kappa B kinase and PI3K-Akt. Carcinogenesis 28(2):363–371 (2007).
Hwang YH, Kang KJ. Conjugated linoleic acid reduces adipose depots without reduction of stearoyl coenzyme A desaturase 1 gene expression. Ann. Nutr. Metab. 51(2):126-133 (2007).
Ip MM, Mcgee SO, Masso-Welch PA, Ip C, Meng XJ, Ou LH, Shoemaker SF. The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium. Carcinogenesis 28(6):1269-1276 (2007).
Javadi M, Geelen MJH, Everts H, Lemmens AG, Beynen AC. Body composition and selected blood parameters in mice fed a combination of fibre and conjugated linoleic acid. J. Anim. Physiol. Anim. Nutr. 91(11-12):492-497 (2007).
Korniluk K, Czauderna M, Kowalczyk J. The influence of dietary conjugated linoleic acid isomers and selenized yeast on the fatty acid profile of the spleen, pancreas and kidneys of rats. J. Anim. Feed Sci. 16(1):121–139 (2007).
Lasa A, Simon E, Churruca I, Fernandez-Quintela A, Rodriguez VM, Portillo MP. Adiposity and serum parameters in hamsters fed energy restricted diets supplemented or not with trans-10,cis-12 conjugated linoleic acid. J. Physiol. Biochem. 63(4):297-304 (2007).
LeDoux M, Laloux L, Fontaine JJ, Carpentier YA, Chardigny JM, Sebedio JL. Rumenic acid significantly reduces plasma levels of LDL and small dense LDL cholesterol in hamsters fed a cholesterol- and lipid-enriched semi-purified diet. Lipids 42(2):135–141 (2007).
Lee K, Paek K, Lee HY, Park JH, Lee Y. Antiobesity effect of trans-10,cis-12-conjugated linoleic acid-producing Lactobacillus plantarum PL62 on diet-induced obese mice. J. Appl. Microbiol. 103(4):1140-1146 (2007).
Liu LF, Purushotham A, Wendel AA, Belury MA. Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin sensitivity, and hepatic steatosis in high-fat-fed mice. Amer. J. Physiol. Gastrointestinal Liver Physiol. 292(6):1671–1682 (2007).
Moloney F, Toomey S, Noone E, Nugent A, Allan B, Loscher CE, Roche HM. Antidiabetic effects of cis-9, trans-11-conjugated linoleic acid may be mediated via anti-inflammatory effects in white adipose tissue. Diabetes 56(3):574-582 (2007).
Navarro V, Macarulla MT, Fernandez-Quintela A, Rodriguez VM, Simon E, Portillo MP. Effects of trans-10,cis-12 conjugated linoleic acid on cholesterol metabolism in hypercholesterolaemic hamsters. European J. Nutr. 46(4):213–219 (2007).
Negrette MS, Montenegro MA, Catuogno MS, Lertora WJ, Guanziroli MC. Decrease of intestinal tumors induced by 1,2-dimethylhydrazine in rats fed with cow milk and buffalo milk. Biocell 31(3):391-396 (2007).
Niedzwiedzka KM, Korniluk K, Kowalczyk J, Czauderna M. Influence of dietary CLA isomers and selenium compounds on the fatty acid and amino acid profiles in blood plasma of rats. J. Anim. Feed Sci. 16(2):257–273 (2007).
Noli C, Carta G, Cordeddu L, Melis MP, Murru E, Banni S. Conjugated linoleic acid and black currant seed oil in the treatment of canine atopic dermatitis: A preliminary report. Veterinary J. 173(2):413-421(2007).
Noto A, Zahradka P, Ryz NR, Yurkova N, Xie XP, Taylor CG. Dietary conjugated linoleic acid preserves pancreatic function and reduces inflammatory markers in obese, insulin-resistant rats. Metab. Clin. Experimental 56(1):142–151 (2007).
Noto A, Zahradka P, Yurkova N, Xie XP, Truong H, Nitschmann E, Ogborn MR, Taylor CG. Dietary conjugated linoleic acid decreases adipocyte size and favorably modifies adipokine status and insulin sensitivity in obese, insulin-resistant rats. Metabolism Clin. Experimental 56(12):1601-1611 (2007).
Park Y, Yang MD, Storkson JM, Albright KJ, Liu W, Cook ME, Pariza MW. Effects of conjugated linoleic acid isomers on serum tumor necrosis factor-a concentration in mice. J. Food Biochem. 31(2):252–265 (2007).
Park Y, Albright KJ, Storkson JM, Liu W, Pariza MW. Conjugated linoleic acid (CLA) prevents body fat accumulation and weight gain in an animal model. J. Food Sci. 72(8):S612-S617 (2007).
Proctor SD, Kelly SE, Stanhope KL, Havel PJ, Russell JC. Synergistic effects of conjugated linoleic acid and chromium picolinate improve vascular function and renal pathophysiology in the insulin-resistant JCR:LA-cp rat. Diabetes Obesity Metab. 9(1):87–95 (2007).
Purushotham A, Shrode GE, Wendel AA, Liu LF, Belury MA. Conjugated linoleic acid does not reduce body fat but decrease hepatic steatosis in adult Wistar rats. J. Nutr. Biochem. 18(10):676-684 (2007).
Purushotham A, Wendel AA, Liu LF, Belury MA. Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice. J. Lipid Res. 48(2):444–452 (2007).
Rahman MM, Bhattacharya A, Banu J, Fernandes G. Conjugated linoleic acid protects against age-associated bone loss in C57BL/6 female mice. J. Nutr. Biochem. 18(7):467–474 (2007).
Rasooly R, Kelley DS, Greg J, Mackey BE. Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. Brit. J. Nutr. 97(1):58–66 (2007).
Ribot J, Portillo MP, Pico C, Macarulla MT, Palou A. Effects of trans-10, cis-12 conjugated linoleic acid on the expression of uncoupling proteins in hamsters fed an atherogenic diet. Brit. J. Nutr. 97(6):1074–1082 (2007).
Ringseis R, Muschick A, Eder K. Dietary oxidized fat prevents ethanol-induced triacylglycerol accumulation and increases expression of PPAR alpha target genes in rat liver. J. Nutr. 137(1):77-83 (2007).
Romero MM, Esteve M, Fernandez-Lopez JA, Alemany M. The conjugated linoleic acid ester of estrone induces the mobilisation of fat in male Wistar rats. Naunyn-Schmiedebergs Arch. Pharmacol. 375(4):283–290 (2007).
Roy A, Chardigny JM, Bauchart D, Ferlay A, Lorenz S, Durand D, Gruffat D, Faulconnier Y, Sebedio JL, Chilliard Y. Butters rich either in trans-10-C18 : 1 or in trans-11-C18 : 1 plus cis-9, trans-11 CLA differentially affect plasma lipids and aortic fatty streak in experimental atherosclerosis in rabbits. Animal 1(3):467–476 (2007).
Russell JS, Mcgee SO, Ip MM, Kuhlmann D, Masso-Welch PA. Conjugated linoleic acid induces mast cell recruitment during mouse mammary gland stromal remodeling. J. Nutr. 137(5):1200–1207 (2007).
Santos-Zago LF, Botelho AP, Costa de Oliveira A. Supplementation with commercial mixtures of conjugated linoleic acid in association with vitamin E and the process of lipid autoxidation in rats. Lipids 42(9):845-854 (2007).
Soel SM, Choi OS, Bang MH, Park JHY, Kim WK. Influence of conjugated linoleic acid isomers on the metastasis of colon cancer cells in vitro and in vivo. J. Nutr. Biochem. 18(10):650-657 (2007).
Tappia PS, Dent MR, Aroutiounova N, Babick AP, Weiler H. Gender differences in the modulation of cardiac gene expression by dietary conjugated linoleic acid isomers. Can. J. Physiol. Pharmacol. 85(3-4):465-475 (2007).
Tsuzuki T, Ikeda T. Slow absorption of conjugated linoleic acid in rat intestines, and similar absorption rates of 9c,11t-conjugated linoleic acid and 10t, 12c-conjugated linoleic acid. Biosci. Biotechnol. Biochem. 71(8):2034-2040 (2007).
Van Nieuwenhove C, Cano PG, Chaia AP, Gonzalez S. Chemical composition and fatty acid content of buffalo cheese from northwest argentina: Effect on lipid composition of mice tissues. J. Food Lipids 14(3):232-243 (2007).
Veaute C, Andreoli MF, Racca A, Bailat A, Scalerandi MV, Bernal C, Borel IM. Effects of isomeric fatty acids on reproductive parameters in mice. Amer. J. Reproductive Immunol. 58(6):487-496 (2007).
Yasui Y, Suzuki R, Kohno H, Miyamoto S, Beppu F, Hosokawa M, Miyashita K, Tanaka T. 9trans,11trans conjugated linoleic acid inhibits the development of azoxymethane-induced colonic aberrant crypt foci in rats. Nutr. Cancer 59(1):82-91 (2007).

Physiological Effects of CLA in Animals: Food/Farm Animals return to top

Aydin R. Effect of dietary oils and conjugated linoleic acid on the growth performance of broilers vaccinated with the La Sota Newcastle vaccine. South African J. Anim. Sci. 37(2):74-80 (2007).
Bolukbasi SC, Erhan MK. The effects of dietary oils on serum lipoprotein and egg quality of hens. Indian Vet. J. 84(3):270–273 (2007).
Castaneda-Gutierrez E, Benefield BC, de Veth MJ, Santos NR, Gilbert RO, Butler WR, Bauman DE. Evaluation of the mechanism of action of conjugated linoleic acid isomers on reproduction in dairy Cows(1). J. Dairy Sci. 90(9):4253-4264 (2007).
Castro N, Acosta F, Capote J, Arguello A. Effect of dietary conjugated linoleic acid on serum levels of N2O5 and L-citrulline in goat kids. Small Ruminant Res. 68(3):333–335 (2007).
Cherian G, Gonzalez D, Ryu KS, Goeger MP. Long-term feeding of conjugated linoleic acid and fish oil to laying hens: Effects on hepatic histopathology, egg quality, and lipid components. J. Appl. Poultry Res. 16(3):420-428 (2007).
Cherian G, Traber MG, Goeger MP, Leonard SW. Conjugated linoleic acid and fish oil in laying hen diets: Effects on egg fatty acids, thiobarbituric acid reactive substances, and tocopherols during storage. Poultry Sci. 86(5):953–958 (2007).
Diez A, Menoyo D, Perez-Benavente S, Calduch-Giner JA, de Celis SVR, Obach A, Favre-Krey L, Boukouvala E, Leaver MJ, Tocher DR, Perez-Sanchez J, Krey G, Bautista JM. Conjugated linoleic acid affects lipid composition, metabolism, and gene expression in Gilthead sea bream (Sparus aurata L). J. Nutr. 137(6):1363–1369 (2007).
dos Santos LD, Furuya WM, Matsushita M, da Silva LCR, Silva TSD, Botaro D. Conjugated linoleic acid (CLA) in Nile tilapia diets: productive performance, chemical and fatty acids composition. Brazilian J. Anim. Sci. 36(5):1481-1488 Suppl. S (2007).
dos Santos LD, Furuya WM, Matsushita M, da Silva LCR, Silva TSDC, Botaro D, Sales PP. Deposition of conjugated linoleic acid (CLA) in Nile tilapia. Brazilian J. Anim. Sci. 36(5):1225-1230 (2007).
Fekete SG, Brown DL. Veterinary aspects and perspectives of nutrigenomics: A critical review. Acta Vet. Hungarica 55(2):229–239 (2007).
Gillis MH, Duckett SK, Sackmann JR. Effects of supplemental rumen-protected conjugated linoleic acid or corn oil on lipid content and palatability in beef cattle. J. Anim. Sci. 85(6):1504–1510 (2007).
Hur SJ, Park GB, Joo ST. Biological activities of conjugated linoleic acid (CLA) and effects of CLA on animal products. Livestock Sci. 110(3):221-229 (2007).
Hur SJ, Park GB, Joo ST. A comparison of the effects of dietary conjugated linoleic acid contents, cholesterol, lipid oxidation and drip loss in pork loin and chicken breast. J. Muscle Foods 18(3):264–275 (2007).
Javadi M, Geelen MJH, Everts H, Hovenier R, Javadi S, Kappert H, Beynen AC. Effect of dietary conjugated linoleic acid on body composition and energy balance in broiler chickens. Brit. J. Nutr. 98(6):1152-1158 (2007).
Kay JK, Mackle TR, Bauman DE, Thomson NA, Baumgard LH. Effects of a supplement containing trans-10, cis-12 conjugated linoleic acid on bioenergetic and milk production parameters in grazing dairy cows offered ad libitum or restricted pasture. J. Dairy Sci. 90(2):721–730 (2007).
Kennedy SR, Bickerdike R, Berge RK, Dick JR, Tocher DR. Influence of conjugated linoleic acid (CLA) or tetradecylthioacetic acid (TTA) on growth, lipid composition, fatty acid metabolism and lipid gene expression of rainbow trout (Oncorhynchus mykiss L.). Aquaculture 272(1-4):489-501 (2007).
Kennedy SR, Bickerdike R, Berge RK, Porter AR, Tocher DR. Influence of dietary conjugated linoleic acid (CLA) and tetradecylthioacetic acid (TTA) on growth, lipid composition and key enzymes of fatty acid oxidation in liver and muscle of At